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Zabetian, Hassan; Sahraei, Reza; Hakimelahi, Hossein; Yusefi, Ali Reza; Sanie, Mohammad Sadegh; Erfanian, Saiedeh; Jahromi, Abdolreza Sotoodeh; Sepidkar, Abdolali; Madani, Abdolhossien; Kafilzadeh, Farshid; Kargar, Mohammad

doi:10.13005/bbra

Cited by 106 publications

(3 citation statements)

References 11,596 publications

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“…Epigallocatechin-3-gallate is the core catechin present in green tea (Suhail, Parveen, Husain, & Rehan, 2019;Tabrez et al, 2020). Various studies reported different bio-physiological properties of EGCG ranging from antioxidative (Lambert & Elias, 2010;Nikoo, Regenstein, & Gavlighi, 2018), cytoprotective (Islam et al, 2020;Moravcova, Cervinkova, Kucera, Mezera, & Lotkova, 2014), antiinflammatory (Byun et al, 2014;Tabrez et al, 2013), and anti-fibrotic (Tsai et al, 2019;Yumei, Zhou, Zheng, & Chen, 2006).…”

Section: Epigallocatechin-3-gallate (Egcg)mentioning

confidence: 99%

“…In a nutshell, higher concentrations of EGCG uncoupled oxidative phosphorylation in mitochondria, damages the outer membrane, thereby stimulating the extrinsic mode of apoptosis (Kucera et al, 2015). Recently, Suhail et al (2019Suhail et al ( & 2020 reported that EGCG binds deep in the DNA binding site of NF-κB and may inhibit NF-κB mediated transcription of target genes (Suhail et al, 2019;Suhail et al, 2020).…”

Section: Epigallocatechin-3-gallate (Egcg)mentioning

confidence: 99%

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Polyphenols as anticancer agents: Toxicological concern to healthy cells

Islam

Suhail

Khan

et al. 2021

Phytotherapy Research

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Polyphenols are a group of diverse chemical compounds present in a wide range of plants. Various biological properties such as antiallergic, antiviral, antibacterial, anticarcinogenic, antiinflammatory, antithrombotic, vasodilatory, and hepatoprotective effect of different polyphenols have been reported in the scientific literature. The major classes of polyphenols are flavonoids, stilbenoids, lignans, and polyphenolic acids. Flavonoids are a large class of food constituents comprising flavones, isoflavanones, flavanones, flavonols, catechins, and anthocyanins sub-classes. Even with seemingly broad biological activities, their use is minimal clinically. Among the other concurrent problems such as limited bioavailability, rapid metabolism, untargeted delivery, the toxicity associated with these polyphenols has been a topic of concern lately. These polyphenols have been reported to result in different forms of toxicity that include organ toxicity, genotoxicity, mutagenicity, cytotoxicity, etc. In the present article, we have tried to unravel the toxicological aspect of these polyphenols to healthy cells. Further high-quality studies are needed to establish the clinical efficacy and toxicology concern leading to further exploration of these polyphenols.

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Section: Epigallocatechin-3-gallate (Egcg)mentioning

confidence: 99%

Section: Epigallocatechin-3-gallate (Egcg)mentioning

confidence: 99%

Polyphenols as anticancer agents: Toxicological concern to healthy cells

Islam

Suhail

Khan

et al. 2021

Phytotherapy Research

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“…The disease has been in Ghana for many years but on other alternative hosts [16]. It was originally identified in Nigeria in 1979 [17], reported in Togo in 1982 [18], and was subsequently reported in Ghana in 1985 [16]. Though the incidence of Phytophthora disease was originally reported in Ghana by 1985, Darkwa (1981) concluded that P.megakarya probably occurred before 1980 until it was officially reported in 1985 at Akomadan-Ashanti Region.…”

Section: Phytophthora Disease In Cocoa Productionmentioning

confidence: 99%

Phytophthora Diseases Prevalence, Its Effects and Controls in Ghana

Frimpong¹,

Ampadu²,

Oppong³

et al. 2021

Agro-Economic Risks of Phytophthora and an Effective Biocontrol Approach

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The success of the UN Sustainable Development Goals in reducing hunger and poverty is limited by crop losses. Globally, plant pests and diseases account for 40% yield losses which threatens food and nutrition security, livelihoods of citizenry and erode the resources of local and national economies. Phytophthora diseases are among the most important diseases in sub-Saharan Africa which result in severe socio-economic consequences. Roots and tubers and cash commodity crops are important staples and foreign exchange earner crops in Ghana which are significantly challenged by the incidence and severity of Phytophthora diseases. To ensure food availability, safeguard the local financial ecosystem and protect the environment, innovative and sound management practices are needed and this chapter reviews the different Phytophthora diseases on crops; more specifically with (cocoa and taro as case studies), the consequences and available management options that can be applied to manage the disease situation in Ghana.

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