Effect of Primary Occlusion Therapy in Asymmetric, Bilateral Amblyopia

Shoshany, Talia N.; Michalak, Suzanne M.; Staffa, Steven J.; Chinn, Ryan N.; Bishop, Kaila; Hunter, David G.

doi:10.1016/j.ajo.2019.10.030

Cited by 14 publications

(6 citation statements)

References 9 publications

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“…This training program also accelerates recovery. Shoshany et al treated 98 bilateral amblyopia cases using optical correction and occlusion and noted the greatest improvement occurred within 12- to 18-months [ 25 ]. These results are similar to our experience in the era of conventional treatment.…”

Section: Discussionmentioning

confidence: 99%

Effects of Vision Therapy on Bilateral Amblyopia Unresponsive to Conventional Treatment: A Retrospective Comparative Study

Lin

Liao

et al. 2022

Children

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Background: In this study we aim to determines the effect of our vision therapy program for 7- to 10-year-old patients who exhibit bilateral amblyopia that is no longer responsive to conventional treatment. Methods: Children with bilateral amblyopia between the ages of 7 and 10 treated with vision therapy at the China Medical University Hospital between 2016 and 2019 were retrospectively reviewed. Age and visual acuity-matched bilateral amblyopes are included as a control group. The visual acuity for both groups showed no improvement for more than 3 months with part-time patching and full refraction correction. The initial and final visual acuity, stereopsis, and refractive status were analyzed. Results: Here, 15 cases were included as the treatment group and 16 cases as a control group. At the endpoint, the study group shows a significant improvement in BCVA, with a mean of 0.32 ± 0.15 logMAR (3 lines improvement) versus 0.003 ± 0.19 logMAR (nearly no improvement) for the control group (p < 0.001). The benefits of treatment are most obvious in the first 3 months after treatment (p < 0.001) and last until the end point. Stereoacuity also improves from 190.00 ± 163.34 to 85.00 ± 61.24 arc seconds, which is a 55.26% improvement. Conclusions: Vision therapy, comprising orthoptic therapy, perceptual learning and dichoptic training, is a successful program for increasing visual acuity and stereoacuity in 7- to 10-year-old children with bilateral amblyopia that is unresponsive to conventional treatment.

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Section: Discussionmentioning

confidence: 99%

Effects of Vision Therapy on Bilateral Amblyopia Unresponsive to Conventional Treatment: A Retrospective Comparative Study

Lin

Liao

et al. 2022

Children

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“…Occlusion therapy is frequently used to treat the disorder; however, it is not suitable for all amblyopic children due to side effects. (Shoshany et al, 2020) Penalization is an alternative treatment that limits the acuity of the dominant eye by cycloplegic agents. This method was initially discovered by Worth, who reported the improvement in acuity in the amblyopic eye after the instillation of atropine in the dominant eye.…”

Section: Discussionmentioning

confidence: 99%

Visual Acuity Assessment With Atropine Penalization vs Partial Occlusion Therapy in Amblyopia Patients in South Punjab

MUZAMIL,

MAJEED,

ATTAULLAH

et al. 2023

Biol Clin Sci Res J

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A retrospective study was conducted in the Ophthalmology Department of Nishtar Medical Hospital from September 2022 to September 2023 to compare the effectiveness of atropine penalization and occlusion therapy in treating amblyopia in children. The study included 50 children aged 2-9 years with no prior treatment history of amblyopia. The children were divided into two groups: Group A received atropine penalization, while Group B received occlusion therapy. Both groups had a mean age of 5.5 years, and all patients passed the visual acuity tests. Strabismus was high in both groups, with 96% in Group A and 92% in Group B. The treatment duration in Group A was 7.5 months on average, while it was 4.5 months in Group B. Treatment compliance was higher in Group A (96%) compared to Group B (68%). After the treatment, the atropine group had a visual acuity range of 6/6 to 6/60, with a mean visual acuity of 6/10. On the other hand, the occlusion group had a visual acuity range of 6/6 to 6/120, with a mean visual acuity of 6/20. The study concluded that atropine penalization had better patient outcomes and compliance in treating amblyopia in pediatric patients. The study concluded that atropine penalization had better patient outcomes and compliance in treating amblyopia in pediatric patients.

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“…In microbial keratitis, the ability of atropine to relieve pain and prevent synechiae formation by mydriasis is beneficial and in clinical use. Topical 1% preparation also has antimicrobial effects that supplement the primary antimicrobial therapy used in keratitis [46,47].…”

Section: Relief Of Accommodative Spasm In Closed Globe Injury and Ker...mentioning

confidence: 99%

“…The different ophthalmic indications may demand different dosages and preparations. Atropine sulfate formulations are commercially available as 0.3%, 0.5%, 1%, and 2% preparations as topical eye drops while the ointment is available as a 1% formulation as shown in the Table 1 [8,46,47,52].…”

Section: Available Ophthalmic Prepara-tion Of Atropinementioning

confidence: 99%

Ophthalmic Uses of Atropine: A Review

Eze

Nathaniel²

2022

JAMMR

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Atropine has been used in medical practice for decades and is one of the essential emergency drugs. Its applications in ophthalmology have also followed a long trajectory. Therefore, this review is intended to explore the various uses of Atropine in ophthalmology. Atropine uses in strict ophthalmic indications have extensive diagnostic and therapeutic outlay including Examination under anesthesia, cycloplegic refraction, myopia, and amblyopic management, post trabeculectomy management, synechiae treatment, floppy iris syndrome, and uveitis management. The side effects have been shown to be dose-dependent with no long-term sequelae. Atropine has remained an important medicine in ophthalmic practice globally.

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Effect of Primary Occlusion Therapy in Asymmetric, Bilateral Amblyopia

Cited by 14 publications

References 9 publications

Effects of Vision Therapy on Bilateral Amblyopia Unresponsive to Conventional Treatment: A Retrospective Comparative Study

Effects of Vision Therapy on Bilateral Amblyopia Unresponsive to Conventional Treatment: A Retrospective Comparative Study

Visual Acuity Assessment With Atropine Penalization vs Partial Occlusion Therapy in Amblyopia Patients in South Punjab

Ophthalmic Uses of Atropine: A Review

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