Effect of PM10 on pulmonary immune response and fetus development

Exploring the Potential Effects and Mechanisms of Asarum sieboldii Radix Essential Oil for Treatment of Asthma

“…Increasing evidence indicates that PM can increase the risk of developing asthma and exacerbate existing asthma. According to previous research, PM 10 inhalation into the airways can promote inflammation, immune response, oxidative stress and airway remodeling in the respiratory tracts via the production of proinflammatory and inflammatory cytokines [ 24 , 25 ]. Considering the recent use of essential oils from natural products to treat respiratory diseases, we constructed a gene set network of AEO and compared it to the asthma-related genes to demonstrate the association between asthma disease and AEO inhalation.…”

Modifiable contributing factors to COVID-19: A comprehensive review

“…Symptoms include impaired memory, cognitive dysfunction, depression, anxiety, and/or vestibular and motor deficits” Rose et al (2017) Neurologic deficits; neurocognitive deficits; COHb; mitochondrial cytochrome c oxidase; glutamate; neuroinflammation; NMDA; oxidative stress; ROS; RNS; HO-1; myeloperoxidase; white matter hyperintensities; hippocampal atrophy Chemotherapy [2]. ICOV “ Meta-analysis of multivariate adjusted OR of death for active chemotherapy was consistently associated with higher risk of death compared to no active chemotherapy …..Active chemotherapy appears to be associated with higher risk of death in cancer patients with COVID-19.” Park et al (2021) COVID-19; risk factor; clinical diagnosis of COVID-19; death; cancer WIS “This case controlled study measured the measles antibody titer in children who survived cancer after chemotherapy to determine the patient's immune status against the measles vaccine …..The cancer survivors had significantly lower measles antibody titers than the healthy control participants, and 78.9% of cancer survivors were unprotected (seronegative) compared to 7.9% in healthy controls …..These results underline the need for post-chemotherapy measles antibody testing and revaccination of seronegative survivors." Abdelaziz et al (2021) measles antibody titer; immune status; humoral immunity IIC “We report the case of a 72-year-old woman with endometrial cancer who was undergoing treatment for hypertension, obesity and diabetes mellitus.…”

“… ICOV “PM10 and NO2 were significantly and positively associated with the risk of a COVID-19 diagnosis (hazard ratio (HR) = 1.44 and 1.16, respectively)." Hutter et al (2020) COVID-19; nitrogen dioxide; particulate matter WIS “inhaled PM10 may induce Th1-shifting immune response in the lung, and that it may affect reproduction (fetus development) by causing lung hypoxia" Park et al (2021) toxicity; total cell number; Th1-dominant immune response; proteins; cell-to-cell communication; IgA; IgE; interval between births of fetuses; number of offspring; neonatal survival rate; sex ratio; stillborn; HIF-1α protein; bronchial epithelial cells; reproduction; lung hypoxia. IIC “We also found a significant short-term association between PM10 and fibrinogen (percent change = 0.17%, 95% CI: 0.04%, 0.29%)."…”

Characterization of water-soluble ions in PM10 over an industrial area in northern Colombia: Temporal variations and correlation with satellite data

“…The Environmental Protection Agency (EPA) and the World Health Organization (WHO) consider particulates, also known as particulate matter (PM), as criteria air pollutants with scientific evidence of posing short- and long-term risks to human health [ 1 , 2 ]. The public health impact of PM has been reported in the last decade [ [3] , [4] , [5] , [6] , [7] ]. Its effects on local climate and ecology have also garnered considerable research interest [ [8] , [9] , [10] , [11] ].…”