2021
DOI: 10.36660/ijcs.20200244
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Abstract: The regular practice of physical exercise as a nonpharmacological treatment of arterial hypertension (AH) has been encouraged due to causing a series of physiological responses in the cardiovascular system, such as the production of vasoactive substances, including nitric oxide (NO). NO is a relaxation factor released by the endothelium, and the decrease in its bioavailability is related to coronary and arterial diseases, such as AH. This study aimed to perform an integrative literature review to elucidate the… Show more

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Cited by 4 publications
(109 citation statements)
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“…30 In addition, PA may be accountable for reducing exercise-induced oxidative stress by producing an increased level of antioxidants, attenuating vascular and cardiac sympathetic activity, dropping serum vasoconstrictor factor levels, and rising endothelial dilating factors that consequently helps in lowering the peripheral vascular resistance and subsuquently leading to improved BP. 16,31 Previous meta-analysis revealed that two most prominent intervention protocols HIIT and CMT were effective in reducing SBP in adults with pre-to established hypertension. 25 Our findings correlate with a study that compared the effects of continuous and interval training in the management of hypertension, whereof researchers found SBP reduction in both experimental groups (-16.4±13.2 mmHg and -13.9±12.6 mmHg respectively).…”
Section: Discussionmentioning
confidence: 99%
“…30 In addition, PA may be accountable for reducing exercise-induced oxidative stress by producing an increased level of antioxidants, attenuating vascular and cardiac sympathetic activity, dropping serum vasoconstrictor factor levels, and rising endothelial dilating factors that consequently helps in lowering the peripheral vascular resistance and subsuquently leading to improved BP. 16,31 Previous meta-analysis revealed that two most prominent intervention protocols HIIT and CMT were effective in reducing SBP in adults with pre-to established hypertension. 25 Our findings correlate with a study that compared the effects of continuous and interval training in the management of hypertension, whereof researchers found SBP reduction in both experimental groups (-16.4±13.2 mmHg and -13.9±12.6 mmHg respectively).…”
Section: Discussionmentioning
confidence: 99%
“…The positive role of exercise training on BP can be perceived through its action on sympathetic activity, enhanced endothelial function and decreased oxidative stress, which cumulatively contributes to the prevention and treatment of hypertension [ 30 ]. In addition, PA may be accountable for reducing exercise-induced oxidative stress by producing an increased level of antioxidants, attenuating vascular and cardiac sympathetic activity, reducing serum vasoconstrictor factor levels and increasing endothelial dilating factors, which that consequently helps in lowering the peripheral vascular resistance and subsequently leads to improved BP [ 16 , 31 ]. A previous meta-analysis revealed that the two most prominent intervention protocols HIIT and CMT were effective in reducing SBP in adults with pre- to established hypertension [ 25 ].…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, the dysfunction of nitric oxide (NO) activity in the brain due to the aging process may also explain the learning impairment ( 101 – 103 ). However, regular PA reshapes the system balance, leading to the regulation of dopamine levels in the brain and the availability of more dopamine receptors ( 104 ), as well as increasing the production of NO release from endothelial cells, favoring vascular function and decreasing NO from inducible NO synthase in the brain ( 103 , 105 , 106 ), potentially reducing the harmful effect of aging. This is evident for active elderly who maintain the associative learning level during RDIF.…”
Section: Discussionmentioning
confidence: 99%