Effect of pH and amphiphile concentration on the gel-emulsion of sodium salt of 2-dodecylpyridine-5-boronic acid: Entrapment and release of vitamin B12

Maiti, Monali; Roy, Aparna; Roy, Sumita

doi:10.1016/j.colsurfa.2014.07.030

Cited by 16 publications

(9 citation statements)

References 42 publications

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“…For this measurement, six pHs in the range from 2 to 7.5 were tried, 40 and absorbance of gel-emulsions were recorded at 550, 664, 433, 590, and 480 nm for vitamin B 12 , methylene blue, cresol red, crystal violet, and doxorubicine, respectively. At pH 2, the entrapped molecules release very fast from the network structures, whereas there was no release in other pHs (pH 2.5, 3.0, 3.5, 5.5, and 7.5) for the amphiphiles.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

Gel-Emulsion Properties of Nontoxic Nicotinic Acid-Derived Glucose Sensor

Roy

Pradhan

et al. 2018

Ind. Eng. Chem. Res.

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Amide linkage containing two nicotinic acid amphiphiles have been investigated for their gel-emulsion and glucose sensing properties. In emulsions, the synthesized materials were used as stabilizers in water medium, whereas organic solvents and/or mineral oils as dispersed phase and water acts as a continuous phase. The gel-emulsions were prepared at room temperature by stirring or shaking, and no heating−cooling arrangement or addition of any other co-solvents or active agents are mandatory. Rheological investigation of these amphiphiles showed mechanical stability of gel-emulsions and its viscoelasticity. Optical images confirmed the existence of network structures in gel-emulsion phase for both amphiphiles. FE-SEM measurement suggests the morphology depends on the solvent:water composition. An XRD study proposed that the arrangements of the amphiphiles in the emulsion state are different. The gel-emulsions formed by the studied amphiphiles are able to entrap and release biomolecules, anticancer drug molecules, and hazards chemicals. These gelator molecules are very sensitive to detect glucose molecules in aqueous solution. The subchronic toxicity of these synthesized molecules has been evaluated as nontoxic on the hematological and biochemical parameters of male Swiss albino mice.

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Section: ■ Results and Discussionmentioning

confidence: 99%

Gel-Emulsion Properties of Nontoxic Nicotinic Acid-Derived Glucose Sensor

Roy

Pradhan

et al. 2018

Ind. Eng. Chem. Res.

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“…The temperature sweep test of glycolipid emulsions at a constant frequency (1 Hz) and strain (1%) is represented in Figure S6. This test is useful to detect the thermotropic behavior of the emulsions . Usually, a rise in temperature causes destabilization of an emulsion, which is indicated by the decrease in G ′ and G ″ values after certain temperature .…”

Section: Resultsmentioning

confidence: 99%

“…To explore the mechanical strength of the emulsions, the storage modulus (G′) and loss modulus (G″) of emulsions were measured as functions of frequency and strain. 39 However, stable emulsions of Y s glycolipids, that is, 3b-9.8 and 3c-9.6, exhibit water (liquid)-like behavior and their rheological analysis was not performed. The frequency sweep test was executed to observe the tolerance to an external force.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

“…This test is useful to detect the thermotropic behavior of the emulsions. 39 Usually, a rise in temperature causes destabilization of an emulsion, which is indicated by the decrease in G′ and G″ values after certain temperature. 26 The maximum G′ and G″ independent temperatures obtained in temperature sweep experiments are listed in Table 2.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

“…Furthermore, water-in-oil emulsions are useful in encapsulating and controlled release of water-soluble bioactives . For pharmaceutical applications, physical encapsulation and release of bioactives from the formulation are the important features. ,− …”

Section: Introductionmentioning

confidence: 99%

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Nonionic Glycolipids for Chromium Flotation- and Emulsion (W/O and O/W)-Based Bioactive Release

Sekhar

Nayak

2018

Langmuir

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Biosourced surfactants are endeavored as a green alternative to biosurfactants and petrochemical surfactants having industrial utilization. Nine glycolipids with headgroup and chain length variation were derived from renewable resources like vegetable oils, carbohydrates, and amino acids. The concentration-dependent interfacial activity, foamability, wetting power, emulsification power, and solubilization capacities of glycolipids were investigated to provide a structure–activity relationship. Later, the metal flotation and emulsification experiments were performed. In general, for metal flotation, the surfactant should contain a hydrophobic tail, hydrophilic head, and chelating function. In the present investigation, it was observed that the headgroup of a glycolipid can serve as a hydrophilic head as well as perform a chelating function. Moreover, heat energy generated from the sunlight was utilized for metal flotation. Additionally, these glycolipids are capable to form stable sunflower oil–water (W/O and O/W) emulsions. The mechanical and thermal stabilities and hydrophobic chain length dependency of the prepared emulsions at different water volume fractions are explored. Furthermore, encapsulation and release of water-soluble (riboflavin and l-ascorbic acid) and oil-soluble (curcumin and α-tocopherol) bioactives in glycolipid emulsions were monitored. Thus, glycolipids under investigation had shown the possibility for pretreatment of chromium-containing wastewaters and bioactive-loaded emulsions toward the controlled release.

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A New Class of Boronic Acid‐Derived Amphiphile‐Based Gel Emulsions Capable of Entrapping and Releasing Vitamin B₁₂ and Doxorubicin

2017

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In this work, two boronic acid based amphiphiles, Sodium salt of 2-amidodecylpyridine-5-boronic acid (SADPB) and Sodium salt of 2-amidododecylpyridine-5-boronic acid (SADDPB) have been synthesized and their gel-emulsion property in organic solvents were investigated. The good gelation ability of the amphiphiles was confirmed by low minimum gelation concentration (MGC) and high gelation number (N gel ) values. Theoretical study established that introduction of amide linkage in the amphiphilic structure dismantles aggregate formation. The gelemulsions are stable towards mechanical and thermal re-sponses. The gelation process is also dependent on the nature of solvent and type of amphiphiles. The morphology of gelemulsions is highly dependent on the concentration of the amphiphile. The prepared gel-emulsions are able to encapsulate and release biomolecule vitamin B 12 and anticancer drug doxorubicin at room temperature. Both vitamin B 12 and doxorubicin exhibited retention of their structures and activity which has been recognized this new type of boronic acid based amphiphiles as efficient drug delivery vehicles.[a] Dr.

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Effect of pH and amphiphile concentration on the gel-emulsion of sodium salt of 2-dodecylpyridine-5-boronic acid: Entrapment and release of vitamin B12

Cited by 16 publications

References 42 publications

Gel-Emulsion Properties of Nontoxic Nicotinic Acid-Derived Glucose Sensor

Gel-Emulsion Properties of Nontoxic Nicotinic Acid-Derived Glucose Sensor

Nonionic Glycolipids for Chromium Flotation- and Emulsion (W/O and O/W)-Based Bioactive Release

A New Class of Boronic Acid‐Derived Amphiphile‐Based Gel Emulsions Capable of Entrapping and Releasing Vitamin B₁₂ and Doxorubicin

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Effect of pH and amphiphile concentration on the gel-emulsion of sodium salt of 2-dodecylpyridine-5-boronic acid: Entrapment and release of vitamin B12

Cited by 16 publications

References 42 publications

Gel-Emulsion Properties of Nontoxic Nicotinic Acid-Derived Glucose Sensor

Gel-Emulsion Properties of Nontoxic Nicotinic Acid-Derived Glucose Sensor

Nonionic Glycolipids for Chromium Flotation- and Emulsion (W/O and O/W)-Based Bioactive Release

A New Class of Boronic Acid‐Derived Amphiphile‐Based Gel Emulsions Capable of Entrapping and Releasing Vitamin B12 and Doxorubicin

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A New Class of Boronic Acid‐Derived Amphiphile‐Based Gel Emulsions Capable of Entrapping and Releasing Vitamin B₁₂ and Doxorubicin