Effect of Perioperative Intravenous Infusion of Lignocaine on Haemodynamic Responses to Intubation, Extubation and Post-Operative Analgesia

Reddy, A. Vishnuvardan; Aasim, Syed Ali; Trivikram, N.

doi:10.21276/apjhs.2017.4.2.4

Cited by 3 publications

(1 citation statement)

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“…Recent studies have demonstrated that perioperative lignocaine infusion is also useful in reducing postoperative pain ( 7 - 10 ). Very few previous studies have demonstrated both the effect of lignocaine infusion that is attenuation of haemodynamic response to intubation and extubation of trachea and postoperative analgesia ( 11 - 13 ). Present trend for perioperative analgesia is multimodal ( 14 ).…”

Section: Introductionmentioning

confidence: 99%

Effect of Perioperative Intravenous Lignocaine Infusion on Haemodynamic Responses and postoperative Analgesia in Laparoscopic Cholecystectomy Surgeries

2018

Anesth Pain Med

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BackgroundDuring general anaesthesia, intubation of trachea and extubation of trachea are often associated with increase in haemodynamic response. Laparoscopic cholecystectomy is a minimal access surgery; postoperatively patients may experience moderate to severe pain. It is well known that lignocaine is useful in attenuating haemodynamic response to intubation and extubation. Previous studies also state that perioperative lignocaine infusion provides postoperative analgesia as well. We hypothesize that perioperative intravenous lignocaine infusion can both attenuate haemodynamic responses to intubation and extubation of trachea and also provide good postoperative analgesia in laparoscopic cholecystectomy surgeries.MethodsDouble blinded randomized controlled trial was undertaken at the department of anesthesia, Sri Siddartha medical college. In group A, 0.9% normal saline was used as placebo for perioperative intravenous infusion. In group B, preservative free 1.5 mg/kg 2 % lignocaine (Loxicard) diluted with normal saline to 1% given at 10 minutes to induction as bolus, followed by an infusion of 1.5 mg/kg/h. till 1 hour postoperatively.ResultsIn Group B there was a statistically less rise in heart rate [HR] and mean blood pressure [MBP] during intubation and extubation of trachea compared to group A. In group B there was a statistically significant increase in the mean pain free period postoperatively compared to group A.ConclusionsPerioperative intravenous infusion of lignocaine attenuates haemodynamic response during the intubation and extubation of the trachea. In addition, it also increases the mean pain free period postoperatively.

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Section: Introductionmentioning

confidence: 99%

Effect of Perioperative Intravenous Lignocaine Infusion on Haemodynamic Responses and postoperative Analgesia in Laparoscopic Cholecystectomy Surgeries

2018

Anesth Pain Med

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Effect of Intravenous Lignocaine on Hemodynamic Variables During Intraoperative and Post-Operative Period

KHANDEKAR,

TITLER,

SHYAMBARAN

et al. 2024

Asian J Pharm Clin Res

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Objectives: The objective of this study was to assess the efficacy of intravenous lignocaine on hemodynamic variables during intraoperative and post-operative periods and in relieving post-operative pain in major abdominal surgery. Methods: To investigate the effects of lidocaine, we designed a double-blind study. We enrolled 100 patients of ASA Grade I or II slated for major abdominal procedures. Each participant received either lidocaine or a saline placebo intravenously. After surgery, we monitored their pain levels, vital signs, and any potential side effects. Results: Our study revealed clear differences in heart rate, blood pressure (both systolic and diastolic), and overall arterial pressure between the lidocaine and placebo groups. Notably, the lidocaine group experienced fewer side effects, such as nausea, vomiting, headache, and shivering, compared to the control group. Conclusion: Intravenous lidocaine reduces intraoperative and post-operative pulse rate and blood pressure in major abdominal surgery. It delays analgesic needs and lowers the incidence of nausea, vomiting, chills, and headache compared to controls.

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Lidocaine Infusion for Hemodynamic Stability-A Case Report in a Child with Moyamoya Disease

Pinho¹,

Cavaleiro²,

Machado³

2017

J Anesth Clin Res

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Effect of Perioperative Intravenous Infusion of Lignocaine on Haemodynamic Responses to Intubation, Extubation and Post-Operative Analgesia

Cited by 3 publications

References 0 publications

Effect of Perioperative Intravenous Lignocaine Infusion on Haemodynamic Responses and postoperative Analgesia in Laparoscopic Cholecystectomy Surgeries

Effect of Perioperative Intravenous Lignocaine Infusion on Haemodynamic Responses and postoperative Analgesia in Laparoscopic Cholecystectomy Surgeries

Effect of Intravenous Lignocaine on Hemodynamic Variables During Intraoperative and Post-Operative Period

Lidocaine Infusion for Hemodynamic Stability-A Case Report in a Child with Moyamoya Disease

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