Effect of oral zinc supplementation on the growth of preterm infants

Islam, M N; Chowdhury, Mak Azad; Siddika, M; Qurishi, S B; Bhuiyan, Mohammod Kamruj Jaman; Hoque, MM; Akhter, S

doi:10.1007/s13312-010-0145-8

Cited by 37 publications

(45 citation statements)

References 12 publications

(19 reference statements)

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“…Islam et al 5 in a trial of Zn supplementation in 100 PT LBW infants for 6 weeks (2 mg/kg) found significant effect on weight as well as on length but the effect on HC was not significant in his study. Hoque et al 11 in 2005 in a study of 200 LBW infants also found significant effect of Zn supplementation on weight gain.…”

Section: Discussionmentioning

confidence: 77%

“…No serious adverse effect was noted related to supplementation therapy 5 . Zinc deficiency in infants has been shown to have an adverse impact on growth and immunity in many studies 2 .…”

Section: Introductionmentioning

confidence: 86%

“…Zinc deficiency in infants has been shown to have an adverse impact on growth and immunity in many studies 2 . Several studies have demonstrated the benefit of zinc supplementation in low birth infants with regard to growth and prevention of infections [2][3][4][5][6][7] However, some studies have shown marginal or no effect 8 , It is with this view that the present study is undertaking to evaluate the effectiveness of zinc supplementation in LBW infants in our set up.…”

Section: Introductionmentioning

confidence: 99%

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To Study the Role of Zinc Supplementation on Growth of Low Birth Weight Infants

Sonawane

Patil

Gulati

et al. 2014

MVP Journal of Medical Science

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This was a randomized controlled trial undertaken to study the role of zinc supplementation on growth of low birth weight infants (b.wt≤2500 gm). Out of 120 LBW infants, 23 were excluded due to loss of follow up. The remaining 97 LBW eligible neonates were randomized in to 2 group (zinc & control group), zinc group were given zinc supplementation at a dose of 2 mg/kg/day for 8 weeks from enrollment. They were then followed up every 4 weeks up to 8 weeks. At each visit, detail anthropometry including e weight, length, and head circumference were recorded at each visit. The infants in the zinc group had significantly higher weight gain (p<0.000), length gain (p<0.000), linear growth velocity and head circumference at 8 weeks. We concluded that zinc supplementation at 2 mg/kg/day for 8 weeks in LBW infants improves their growth during infancy.

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Section: Discussionmentioning

confidence: 77%

“…No serious adverse effect was noted related to supplementation therapy 5 . Zinc deficiency in infants has been shown to have an adverse impact on growth and immunity in many studies 2 .…”

Section: Introductionmentioning

confidence: 86%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

To Study the Role of Zinc Supplementation on Growth of Low Birth Weight Infants

Sonawane

Patil

Gulati

et al. 2014

MVP Journal of Medical Science

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“…Autorzy badań sugerują, że w takim przypadku wskazane jest stosowanie cynku w dawce około 10 mg na dobę. Należy jednak zaznaczyć, że równolegle powinna być stosowana suplementacja innych minerałów (głównie miedzi i żelaza), gdyż zwiększona podaż cynku może prowadzić do ich niedoboru [47,48]. Kolejnym wskazaniem do wprowadzenia suplementacji cynku jest ostra biegunka występująca u noworodków, niemowląt i dzieci w wielu krajach rozwijają-cych się.…”

Section: Suplementacja Preparatami Cynkuunclassified

Importance of zinc for the human body in the aspect of zinc supplementation

Mońka

Wiechuła

2017

Ann. Acad. Med. Siles.

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ST R ES ZCZ E NI ECynk jest jednym z głównych pierwiastków śladowych organizmu, spełniającym rolę katalityczną, strukturalną i regulacyjną. Jest niezbędny do podziałów komórkowych i różnicowania powstających komórek, uczestniczy w homeostazie, reakcjach odpornościowych, w apoptozie i starzeniu się organizmu. Cynk jest również składnikiem wielu enzymów i białek oraz odgrywa ważną rolę w spermatogenezie i syntezie hormonów steroidowych. Niedostateczna podaż cynku dotyczy ok. 30% ludności świata. Oprócz niedostatecznej podaży z pokarmem, przyczyną niedoboru cynku mogą być niektóre schorzenia oraz nieprawidłowe wchłanianie tego pierwiastka. Schorzenia, wynikające z niedoboru tego pierwiastka, mogą występować zarówno u dzieci, jak i dorosłych. Suplementacja diety preparatami cynku w wielu przypadkach jest niezbędna, jednak samodzielne jego stosowanie, bez stwierdzonego niedoboru i bez konsultacji z lekarzem, może doprowadzić do występowania działań niepożądanych w wyniku jego nadużywania, w tym także niebezpiecznych interakcji z innymi stosowanymi preparatami i żywnością. S Ł O W A K L U C Z O W Esuplementacja, znaczenie cynku dla organizmu, niedobór cynku, toksyczność cynku AB ST R ACTZinc is one of main trace elements of the body, that plays a catalytic, structural and control role. It is essential for cell division and the differentiation of arising cells, it is involved in homeostasis, immunological reactions, in apoptosis and ageing of the body. Zinc is also an element of many enzymes and proteins, and it is important in the spermatogenesis and synthesis of steroidal hormones as well as. About 30% of the world's population suffers from an insufficient supply of zinc. Apart from an insufficient supply from food, some diseases and abnormal absorption of this element can be a cause of zinc deficiency. Diseases resulting from zinc deficiency may appear both in children and adults.

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“…In this issue of Indian Pediatrics, Islam and colleagues report the findings of a double blind randomized controlled trial evaluating the efficacy of oral zinc supplementation on the growth of hospital born preterm infants in the Neonatal Special Care Unit of Dhaka in Bangladesh (2). This is the first study carried out selectively among preterm babies to evaluate the effect of zinc supplementation in a developing country setting.…”

Section: E D I T O R I a L E D I T O R I A L E D I T O R I A L E D I mentioning

confidence: 99%