Effect of non-alcohol beer on anxiety: Relationship of 5-HIAA

Abstract

Beer contains hop (Humulus lupulus L.) as flavoring and preservative. This cannabaceae plant, which possesses sedative and hypnotic properties, is present in non alcoholic beer as well. Likewise regular beer, non alcoholic beer includes the essential amino acid lysine with relaxing effects, which are related to the inhibition of serotonin receptors. It is known that the main neuroendocrine signal from stress is the release of the hormone cortisol, alongside with the altered levels of the hormone melatonin and the neurotransmitter serotonin. In this study we aimed to analyze the possible anxiolytic effect of non alcoholic beer on neuroen docrine levels of cortisol, melatonin and serotonin, in a population under stress. To achieve this goal, a healthy student population was enrolled under the stressful conditions evoked by official academic exams. They consumed 1 non alcoholic beer (330 mL) at dinner time for 14 nights. Melatonin, serotonin and cor tisol levels were measured by quantifying their early morning urinary metabolites collected weekly. The con sumption of non acoholic beer reduced significantly the nocturnal serotonin levels whereas there were no substantial changes on melatonin and cortisol levels. However and in line with this, Anxiety/State parameters underwent a significant decreased after consumption of non alcoholic beer at dinner time regarding to con trol values. These results point to the anxiolytic response of non alcoholic beer is performed through the sero toninergic pathway. All in all, consumption of non alcoholic beer might be an additional tool to deal with serotonin related stress profile.

Drinking Behavior, Taste Preferences and Special Beer Perception among Romanian University Students: A Qualitative Assessment Research

“…All these studies came to the same conclusion: that drinking 330 mL of NAB during evening meals on two weeks may decrease feelings of anxiety and stress. These results are promising, but it must be stressed related research is still at an early stage [ 59 ]. A non-alcoholic beer component, β-pseudouridine, was found to be a potent protector against the damage caused by radiation (radioprotective effect) [ 60 , 61 ].…”

“… Potential properties of beer’s nonalcoholic fractions [ 13 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 ]. …”

Current Opinions in Chrononutrition and Health

“…Moreover, the sensitivity of GABA receptors, may be modulated by ingest of hops or other plants. In some research carried out with non-alcohol beer in a moderated consumption at night it provokes beneficial changes in both anxiety and depression in stressed populations [7,8].…”

Functionality of Special Beer Processes and Potential Health Benefits

“…The Czech Republic shows the highest per head consumption, with more than 150 L per year, followed by Austria, Poland, and Germany with more than 100 L/head/year [6]. Recently, studies have shown that moderate beer consumption can have anti-inflammatory and antioxidant properties [7,8], presents certain benefits for bone density [9], and may also prevent coronary heart disease [10][11][12]. Beer compounds that contribute to its functional properties are mainly antioxidants.…”