EFFECT OF Nigella sativa SEEDS DIETARY SUPPLEMENTATION ON OOCYTE MATURATION AND EMBRYO DEVELOPMENT IN MICE

Effects of Dietary Microalgae Supplementation on Mammals’ Production and Health

“…Stimulation of ovarian activity or treatment of dysfunctions was widely investigated through nutritional levels and ingredients (Nagasawa et al, 1989;Downing et al, 1995;Mohammed et al, 2005;Mohammed and Attaai, 2011;Gifre et al, 2017;Senosy et al, 2017Senosy et al, , 2018Mohammed, 2019;Mohammed et al, 2012Mohammed et al, , 2021Mohammed and Farghaly, 2018;Mohammed and Al-Hozab, 2020;Ali et al, 2021), hormonal supplementation (Zarazaga et al, 1996;, both hormonal and nutritional supplementation (Mohammed and Attaai, 2011). Because of the negative effects of increased energy and protein in the diet for humans and animals on health and fertility (McEvoy et al, 1997;Dawuda et al, 2002;Mohammed et al, 2012) and the high cost of diet, microalgae and their purified extracts were given in small quantity as replacers of hormonal stimulation.…”

Leverage of Moringa oleifera Supplementation on Performances, Biochemical, and Milk Profiles in Mammals

“…They attributed the differences between the results to the difference in the environmental conditions, the species, and the age of the animals, as well as the composition and levels of supplementing M. oleifera. Gonadal dysfunctions and reproductive hormonal imbalances were widely modulated through nutritional ingredients (Nagasawa et al, 1989;Downing et al, 1995;Mohammed and Attaai 2011;Gifre et al, 2017;Senosy et al, 2017Senosy et al, , 2018Mohammed and Farghaly 2018;Mohammed 2018;Mohammed 2019;Mohammed et al, 2012Mohammed et al, , 2020Al-Hozab 2020;Ali et al, 2021), hormonal supplementation (Zarazaga et al, 1996;, and both hormonal and nutritional supplementation (Mohammed and Attaai, 2011). Based on the negative influences of increased energy and protein in the diets of humans and animals on health and fertility (McEvoy et al, 1997;Dawuda et al, 2002;Mohammed et al, 2012), and because of the high cost of diet; M. oleifera and their purified extracts were given in small quantity as replacers instead of hormonal stimulation (Odeyinka et al, 2008).…”

Changes in Nucleus and Cytoplast During Oocyte Maturation: Involvement in Embryo Production

“…Between the period of LH surge and ovulation, the fully grown germinal vesicle oocyte of pre-ovulatory follicle undergoes several changes in its GV nucleus and cytoplast known as oocyte maturation. The first sign of resumption of meiotic maturation is GVBD, which occurred approximately 2h of starting maturation in mouse oocytes (Gao et al, 2002;Mohammed et al, 2008;Mohammed et al, 2010;Mohammed et al, 2019;Mohammed and Farghaly, 2018), and thereafter the chromosomes condense, microtubules pull the chromosomes to form the metaphase I (MI) plate. The 2 nd meiotic division occurs immediately without chromosome replication and the oocyte reaches the MII stage.…”

“…The in vitro maturation of mouse oocyte needs approximately 15-17 hr. (Mohammed and Farghaly, 2018;Mohammed et al, 2008;Mohammed et al, 2010;Mohammed et al, 2019). The cytoplasmic and nuclear changes that occur during maturation of oocyte are important for successful fertilization and embryo development (Mohammed, 2014a;Mohammed et al, 2014b;Mohammed and Farghaly, 2018;Mohammed et al, 2019a;Saini et al, 2022).…”

“…(Mohammed and Farghaly, 2018;Mohammed et al, 2008;Mohammed et al, 2010;Mohammed et al, 2019). The cytoplasmic and nuclear changes that occur during maturation of oocyte are important for successful fertilization and embryo development (Mohammed, 2014a;Mohammed et al, 2014b;Mohammed and Farghaly, 2018;Mohammed et al, 2019a;Saini et al, 2022). Changes of maturation promoting and cytostatic factors in addition to two asymmetrical meiotic divisions resulting in a single oocyte and polar bodies for oocyte maturation.…”