Effect of NaF, SnF₂, and TiF₄Toothpastes on Bovine Enamel and Dentin Erosion-Abrasion In Vitro

Abstract

The aim of this study was to compare the effect of toothpastes containing TiF4, NaF, and SnF2 on tooth erosion-abrasion. Bovine enamel and dentin specimens were distributed into 10 groups (n = 12): experimental placebo toothpaste (no F); NaF (1450 ppm F); TiF4 (1450 ppm F); SnF2 (1450 ppm F); SnF2 (1100 ppm F) + NaF (350 ppm F); TiF4 (1100 ppm F) + NaF (350 ppm F); commercial toothpaste Pro-Health (SnF2—1100 ppm F + NaF—350 ppm F, Oral B); commercial toothpaste Crest (NaF—1.500 ppm F, Procter & Gamble); abrasion without toothpaste and only erosion. The erosion was performed 4 × 90 s/day (Sprite Zero). The toothpastes' slurries were applied and the specimens abraded using an electric toothbrush 2 × 15 s/day. Between the erosive and abrasive challenges, the specimens remained in artificial saliva. After 7 days, the tooth wear was evaluated using contact profilometry (μm). The experimental toothpastes with NaF, TiF4, SnF2, and Pro-Health showed a significant reduction in enamel wear (between 42% and 54%). Pro-Health also significantly reduced the dentin wear. The toothpastes with SnF2/NaF and TiF4/NaF showed the best results in the reduction of enamel wear (62–70%) as well as TiF4, SnF2, SnF2/NaF, and TiF4/NaF for dentin wear (64–79%) (P < 0.05). Therefore, the experimental toothpastes containing both conventional and metal fluoride seem to be promising in reducing tooth wear.

Titanium Tetrafluoride (TiF4) in the Treatment of Dental Erosion

“…Among them fluorides may be cited 19,20 , the use of antacid solutions 21 , high potency lasers 22 , adhesives 23 and sealants 24 . Fluorides are known to form a layer of mineral precipitates on the dental surface 6 .…”

“…For this purpose, therapies with agents with high concentrations of fluorides or applications with prolonged time have been shown to be more efficient, since they are able to form thicker, dense and stable layers of CaF 2 -like compounds 25 . Although, the protection conferred by fluoride compounds commonly used to prevent carious lesions, such as sodium fluoride and amine fluoride, have still been shown to be limited in cases of erosion 20,26 . For this reason, compounds containing polyvalent metal cations combined with fluorides have been tested.…”

“…Since TiF 4 enables the formation of this acid-resistant layer, it is responsible for the production of a diffusion barrier and a reservoir of F ions, which may delay the dissolution of dental tissue exposed to acidic challenges 25 . For this reason, its effect on erosion has been studied and has obtained promising results in both enamel 19,20,30,39,42 and dentin 43 . These results are dependent on the concentration, form of presentation, pH and time of application of TiF 4 26,30,39 .…”

Influência da frequência de aplicação da solução de AmF/NaF/SnCl2 no seu potencial em inibir a progressão da lesão de erosão no esmalte dental humano

“…Visto que o efeito anti-erosivo de fluoretos convencionais, como fluoreto de sódio Levy et al, 2012;Comar et al, 2012;Mathews et al, 2012) e fluoreto de amina (Vieira et al, 2005;Ganss et al, 2010b), requer um regime de fluoretação intensivo (Ganss et al, 2004), e ainda assim têm potencial limitado contra a erosão , estudos recentes têm se focado em compostos de fluoretos mais eficazes (Magalhães et al, 2011b;Ganss et al, 2012;. Neste contexto, os compostos contendo íons metálicos polivalentes combinados a fluoretos vêm sido testados, tais como titânio, estanho, cobre, zinco, alumínio e ferro (Schlueter et al, 2009c).…”

“…Dentre eles, preparações contendo estanho associado a fluoretos provaram ser muito eficazes na redução da desmineralização erosiva (Ganss et al 2004(Ganss et al , 2008(Ganss et al , 2010a(Ganss et al , 2010b(Ganss et al , 2012b(Ganss et al , 2014(Ganss et al , 2015Schlueter et al, 2009aSchlueter et al, , 2009bSchlueter et al, , 2009cSchlueter et al, , 2009dSchlueter et al, , 2009e, 2010Schlueter et al, , 2011aSchlueter et al, , 2013Schlueter et al, , 2014Hove et al, 2006Wiegand et al, 2009;Yu et al, 2010aYu et al, , 2010bComar et al, 2012;Huysmans et al, 2011;Stenhagen et al, 2013;Rakhmatullina et al, 2013;Lussi, 2014).…”