Effect of Mexidol-Vet® on the course and outcome of acute radiation injury in rats

Abstract

This paper presents experimental data on the effect of the drug Mexidol-Vet® on the course and outcome of acute radiation damage in rats caused by a single, general, external gamma radiation. There was a 20 % decrease in mortality in animals relative to the control values, activation of erythropoiesis, and a decrease in the severity of erythrocytopenia, leukocytopenia, and thrombocytopenia with the use of Mexidol-Vet®. The supposed mechanism of radioprotective and therapeutic action is the pronounced antioxidant and membrane-protective properties of the drug.