Effect of Medicinal Plants on Haematology and Serum Biochemical Parameters of Village Chickens Naturally Infected with <i>Heterakis gallinarum</i>

Abstract

The effects of Aloe ferox, Agave sisalana and Gunnera perpensa on haematological and biochemical parameters of village chickens naturally infected with Heterakis gallinarum were evaluated. One hundred and twelve mature village chickens were randomly allotted into 14 groups of 8 chickens. Group 1 and 2 were orally administered 1 mL distilled water for 4 consecutive days and 1 mL mebendazole (once), respectively. Groups 3-6 received 1 mL orally of aqueous leaf extract of A. ferox for 4 consecutive days, groups 7-10 A. sisalana and 11-14 G. perpensa in graded doses of 50, 100, 200 and 400 mg/kg, respectively. Blood was collected into vacutainers in triplicate, from the wing veins on day 0, 7 and 14. Data was analysed using general linear model of statistical analyses system. Chickens offered A. sisalana (200 mg/kg) had highest alanine transaminase (ALT) value (P &lt; 0.05; 7.50 ± 0.406 U/l) on day 0. On day 7 and 14, there was no difference in ALT values (P &gt;0.05). Significant differences among plants for aspartate transaminase on day 0, 7 and 14 were observed. Mean corpuscular haemoglobin concentration and mean corpuscular volume were maintained within the reference range. From day 0 to 14, haematocrit was reduced for chickens on G. perpensa (50, 100 and 400 mg/kg), A. ferox (100 and 400 mg/kg) and A. sisalana (50, 100, 200 and 400 mg/kg). Haemoglobin was out of range on day 0 and improved to be within the range on day 7 and 14. The medicinal plants enabled normal synthesis and functioning of haematological and biochemical parameters of village chickens and were maintained within the expected reference ranges. These plants are crucial phytomedicines for treating H. gallinarum infestations in village chickens.DOI: http://dx.doi.org/10.3329/bjvm.v12i2.21263Bangl. J. Vet. Med. (2014). 12 (2): 99-106

From Traditional Usage to Pharmacological Evidence: Systematic Review of Gunnera perpensa L.

“…Mwale et al [70] evaluated the haematological and serum biochemical parameters of G. perpensa aqueous leaf extract in village chickens naturally infected with Heterakis gallinarum . From day 0 to 14, haematocrit was reduced for chickens orally administered with G. perpensa 50, 100, and 400 mg/kg doses and haemoglobin was out of the range on day 0 and improved to be within the range on days 7 and 14.…”

Effect of Moringa oleifera leaf extract on the haematological and serum biochemistry of rabbits reared in a semi-humid environment

“…Such medicinal plants include, Aloe ferox V (Mwale et al, 2014), Telfaria occidentalis (Dada and Abiodun, 2014) and Moringa oleifera (Ojo et al, 2015). The effects of any feed ingredient including medicinal plants on the haematological factors of the livestock are of immense assistance in deciding whether or not such a feed ingredient will be safe as feedstuff (Mitruka and , 1997).…”

Sub-Acute Toxicity Effects of Methanolic Stem Bark Extract of Entada abyssinica on Biochemical, Haematological and Histopathological Parameters in Wistar Albino Rats

“…The significant effect on red blood cell differentials indicated that the extract affected the process of erythropoiesis probably by the phytochemicals interfering with the secretion and/or activity of erythropoietin ( Awe and Banjoko, 2013 ; Mugisha et al, 2014 ; Zaruwa et al, 2016 ). Diminished levels of mean platelet volume and procalcitonin could probably be due to presence of toxic phytochemicals that interfere with the functioning of thrombopoietin or cause inflammation of the bowel ( Mwale et al, 2014 ). The significant lowering of the pH indicated the potential of the extract to cause acidosis probably by stimulating the secretion of hydrogen ions into blood and/or inhibiting their renal excretion.…”