Effect of maternal age on reproductive capacity

The influence of an essential fatty acid deficient-diet on the reproductive performance of female rats

“…It is interesting to note that changes in the reproductive function, as found in our EFAD rats, are similar to those observed in ageing female rodents fed a commercial diet (Talbert, 1968 …”

Delay in Ovulation and Fertilization and Asynchronous Pronuclear Development in Aged Hamsters.

“…However, there was no difference between the mean number of ova collected from aged hamsters at 2 h after the estimated time of ovulation and those collected from young females at 1 h. The delay in ovulation is probably caused by an interplay of many agerelated changes in several organs. Physiological factors related to such alterations in aged females may include changes in tissue and organ sensitivity to the anterior pituitary secretions, changes in ovarian function, and progressive hormonal imbalance of several organs [1][2][3][4][5][6].…”

Ovarian Support of Pregnancy in Ageing Inbred Mice

“…The average litter size of female mice declines with increasing age and breeding ceases well before the end of the life-span (Talbert, 1968). This reduced fertility of old mice cannot be attributed to a decline in ovulation rate since the number of CL of pregnancy remain high (Biggers, Finn & McLaren, 1962;Harman & Talbert, 1970).…”