Effect of manganese on thyroid function in sheep

Badiei, Khalil; Mostaghni, K.; Gorjizadeh, E.

doi:10.1007/s00580-008-0737-z

Cited by 7 publications

(9 citation statements)

References 24 publications

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“…This may be due to thrombocytopenia and thrombocytosis after chronic lead intoxication (Sudakova et al, 1983;Mugahi et al, 2003;Abdulkareem, 2010); while the insignificant increase in the white blood cell may be due to lead induced inflammation (Yagminas et al, 1990, Alwaleedi, 2015.Significant increase in ALT and AST which are biomarkers for liver toxicity was observed in this study (P<0.05), might be due to increased cell membrane permeability, increased cellular basal metabolic rate or cell membrane damage of hepatocytes caused by lead acetate. These results agree with previous studies reported an elevation in AST and ALT levels after treatment with lead due to acute hepatitis, jaundice, and liver cirrhosis in mice, human and rat (Mehta et al, 2002;Patil et al, 2007;Shalan et al, 2005, Alwaleedi, 2015, also in sheep (Badiei et al, 2009). The significant decrease in albumin at the reparatory phase E3 J. Med.…”

Section: Discussionsupporting

confidence: 92%

Effects of lead on Epidermal wound Contraction and serum biochemistry in West African dwarf goats

Olaifa¹,

Adewoye²,

Akpan³

2016

EJMR

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Lead contamination through wound could either be environmental and or systemic sources that impair wound healing in animals. The haematological, biochemical changes including thewound healing effects of topical lead poisoning were therefore investigated using ten adult West African dwarf (WAD) goats, randomly divided into two groups of five animals each. The first group served as the control and the second group was treated with lead chloride solution. Wound contraction was compared between the two groups, haematology and serum biochemistry were analysed at each stage of the healing process. The results revealed a delay in wound contraction in the lead treated group. Erythrocyte sedimentation rate, haemoglobin concentration, packed cell volume, albumin, neutrophil count in the lead treated group decreased significantly (P<0.05).Heart rate and temperature increased significantly (P<0.05, P<0.01) in the treated group. This study concluded that epidermal lead exposure impaired wound healing.

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Section: Discussionsupporting

confidence: 92%

Effects of lead on Epidermal wound Contraction and serum biochemistry in West African dwarf goats

Olaifa¹,

Adewoye²,

Akpan³

2016

EJMR

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“…Concentrations of T3 and T4 in gimmers were similar to values mentioned in literature. Contents of FT3 and FT4 were in ewes lower that those given by for example Nazifi et al (2008) or Badiei et al (2010). Individual maximum values that over-exceeded 3.5 ng/ml in both groups of gimmers would imply latent hypothyroidism in humans.…”

Section: Discussionmentioning

confidence: 73%

“…When comparing the concentrations of T4, T3 FT3 and FT4 in both groups of ewes in our study, the concentration of free forms of hormones are lower according to Nazifi et al (2008), Badiei et al (2010) or Eshratkhah et al (2011). Concentrations of hormones found in both groups of ewes corresponded to lowered activity of the thyroid gland as demonstrated by histological findings, too.…”

Section: Discussionmentioning

confidence: 82%

Histometric and biochemical properties of the thyroid gland in sheep with high iodine supplementation

et al. 2013

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The aim of this study was to evaluate histometric and biochemical properties of the thyroid gland of sheep supplemented with high doses of iodine. The study was conducted on ewes (n = 12) and gimmers (n = 12) of Sumava mountain sheep; each group was subdivided into two groups (group A and B) of six animals. Feed of group A was supplemented with 3 mg iodine/kg of dry matter; group B was given 5 mg iodine/kg dry matter. The iodine in feed mineral supplement was in the form of calcium iodide. The ewes were at first carrying, subsequently lambing, lactating and finally remained barren. The experiment ended after 11 months, when all animals were slaughtered and a sample of the thyroid gland was taken for histometric examination and determination of iodine content by modified colorimetric method. Prior to the slaughter, blood samples were collected for determination of thyroidal hormones and the thyroid-stimulating hormone in blood serum. Thyroid glands of sheep from group B showed higher thyroid weight, larger follicles, higher percentage of large follicles and lower follicular cells compared to groups A. Normal or lower content of triiodothyronine and thyroxine, lower content of their free fractions and bordering or elevated concentrations of thyroid-stimulating hormone were detected in blood serum of all four groups. This trend can signalize the tendency of lowering activity of the thyroid gland. The results of this long-term study show impacts of higher iodine intake on the structure and function of the thyroid gland in sheep.

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“…The chief secretory hormone in adult sheep is T4. Several factors influence thyroid function: e.g seasonal changes, reproductive status, age and mercury-induced hypothyroidism [15][16][17] . Although related research is abundant, investigations of Babesiosis-induced blood profile alterations are scarce.…”

Section: Introductionmentioning

confidence: 99%

Babesiosisli Koyunlarda Plazma Malondialdehid, Tiroid Hormonları ve Bazı Kan Profilleri

Azimzadeh¹,

Nouri²,

Farooghi³

et al. 2013

Kafkas Univ Vet Fak Derg

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Effect of manganese on thyroid function in sheep

Cited by 7 publications

References 24 publications

Effects of lead on Epidermal wound Contraction and serum biochemistry in West African dwarf goats

Effects of lead on Epidermal wound Contraction and serum biochemistry in West African dwarf goats

Histometric and biochemical properties of the thyroid gland in sheep with high iodine supplementation

Babesiosisli Koyunlarda Plazma Malondialdehid, Tiroid Hormonları ve Bazı Kan Profilleri

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