Effect of magnesia on the degradability and bioactivity of sol–gel derived SiO2–CaO–MgO–P2O5 system glasses

Ma, Jie; Chen, C.Z.; Wang, Diangang; Jiao, Yue; Shi, Jiazi

doi:10.1016/j.colsurfb.2010.06.022

Cited by 90 publications

(56 citation statements)

References 53 publications

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“…The presence of MgO in the glass B32 caused a slightly lower solubility of the same until seven days of immersion in SBF solution. This lower glass degradability may arise not only from the higher energy of Mg–O bond, limiting its reactivity and ion leaching, but also from the role of this oxide in glass network, that may to act either as a glass modifier or as an intermediate oxide [35,51]. After 14 days immersion in SBF solution, this glass presents a slightly higher solubility that may be linked with an increased kinetics of ionic exchange between the glass and SBF solution at this stage, which is in accordance with the pH changes observed for this same time period (Figure 9).…”

Section: Resultsmentioning

confidence: 99%

Bioactive Glasses with Low Ca/P Ratio and Enhanced Bioactivity

et al. 2016

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Three new silica-based glass formulations with low molar Ca/P ratio (2–3) have been synthesized. The thermal properties, the crystalline phases induced by thermal treatments and the sintering ability of each glass formulation have been investigated by simultaneous differential scanning calorimetry-thermogravimetric analysis (DSC-TG), X-ray diffraction (XRD) and hot stage microscopy (HSM). The glasses exhibited a good sintering behavior, with two samples achieving shrinkage of 85%–95% prior to crystallization. The bioactivity of the glasses in simulated body fluid (SBF) has been investigated by performing XRD and Fourier transform infrared spectroscopy (FTIR) on the samples prior and after immersion. The glasses with lower MgO contents were able to form a fully crystallized apatite layer after three days of immersion in simulated body fluid (SBF), while for the glass exhibiting a higher MgO content in its composition, the crystallization of the Ca–P layer was achieved after seven days. The conjugation of these properties opens new insights on the synthesis of highly bioactive and mechanically strong prosthetic materials.

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Section: Resultsmentioning

confidence: 99%

Bioactive Glasses with Low Ca/P Ratio and Enhanced Bioactivity

et al. 2016

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“…When phosphate is present (usually using the precursor triethylphosphate) in a silica sol-gel glass, it is present as orthophosphate, as it is in the melt-derived glasses [152]. Replacing calcium with magnesium can also reduce the dissolution rate of the glass and therefore its bioactivity, perhaps due to the magnesium behaving as a network intermediate [153][154][155].…”

Section: Atomic Structure Of Bioactive Glass and Its Relation To Dissmentioning

confidence: 99%

Reprint of: Review of bioactive glass: From Hench to hybrids

2015

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“…The typical 60SiO 2 -36CaO-4P 2 O 5 (in mol%; termed 58S) system has been studied extensively and this system produced by a sol-gel technique was more bioactive than the meltquenching BG of the same composition [2]. SiO 2 -CaO-P 2 O 5 system incorporated with ZnO, MgO, and SrO as network modifiers demonstrated the effect of slowing down the degradation of the material [3][4][5][6]. Additional drawbacks found in several families of porous silicate-based BG materials such as high liquidus temperature, high brittleness and low biodegradation rate limit their applications where load bearing is required [7][8][9][10].…”

Section: Introductionmentioning

confidence: 98%