Effect of low power laser irradiation on disconnecting the membrane-attached hemoglobin from erythrocyte membrane

Mi, X.Q.; Chen, J.Y.; Zhou, Leyuan

doi:10.1016/j.jphotobiol.2005.12.018

Cited by 26 publications

(17 citation statements)

References 15 publications

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“…They hypothesized that the 'mobilization' of membrane-linked hemoglobin might cause this enhancing effect, which has been demonstrated in their later porcine study [24].…”

Section: Discussionmentioning

confidence: 93%

“…Important influencing factors are the oxygenation, the temperature, the pH and the osmolarity of the micro-environment of the red blood cells [1,3,11]. Irradiation of various origins may interact with these factors at numerous points, by influencing the cell volume, the membrane integrity by oxidative damage and structural changes [7,10,15,24,29,32]. Since red blood cell deformability plays important role in determining blood flow and microcirculation [1,8,19,20], these changes may cause further alteration in tissue perfusion.…”

Section: Discussionmentioning

confidence: 99%

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Early micro-rheological consequences of single fraction total body low-dose photon irradiation in mice

Szluha

Lazányi

Furka

et al. 2014

Clinical Hemorheology and Microcirculation

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Despite of the studies on widespread biological effects of irradiation, surprisingly only little number of papers can be found dealing with its in vivo hemorheological impact. Furthermore, other studies suggested that low-dose irradiation might differ from high-dose in more than linear ways. On Balb/c Jackson female adult mice hematological and hemorheological impacts of total body irradiation were investigated 1 hour following 0.002, 0.005, 0.01, 0.02, 0.05 and 0.1 Gy dose irradiation. In case of 0.01 Gy further groups were analyzed 30 minutes, 2, 4, 6, 24 and 48 h after irradiation. According to the results, it seems that the dose-dependent changes of blood micro-rheological parameters are not linear. The irradiation dose of 0.01 Gy acted as a point of 'inflexion', because by this dose we found the most expressed changes in hematological parameters, as well as in red blood cell aggregation, deformability and osmoscan data. The time-dependent changes showed progressive decrease in pH, rise in lactate concentration, further decrease in erythrocyte aggregation index and deformability, with moderate shifting of the optimal osmolarity point and modulation in membrane stability. As conclusion, low-dose total body irradiation may cause micro-rheological changes, being non-linearly correlated with the irradiation dose.

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“…They hypothesized that the 'mobilization' of membrane-linked hemoglobin might cause this enhancing effect, which has been demonstrated in their later porcine study [24].…”

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Early micro-rheological consequences of single fraction total body low-dose photon irradiation in mice

Szluha

Lazányi

Furka

et al. 2014

Clinical Hemorheology and Microcirculation

View full text Add to dashboard Cite

show abstract

“…Study by Heu et al 8 failed to find any change in local circulation in healthy tissues. Interestingly, an older study by Mi et al 10 suggested that laser may increase the deformability of the erythrocyte molecule with implications for both increasing the rate of erythrocyte flow through peripheral capillary beds and availability of the hemoglobin molecule within the red blood cells.…”

Section: Effect On Vasodilationmentioning

confidence: 99%

Low-level Laser Therapy: A Literature Review

Kohale¹,

Agrawal²,

Sope³

et al. 2015

International Journal of Laser Dentistry

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1 IJoLD ABSTRACT LASER is an acronym for "Light Amplification by Stimulated Emission of Radiation." The arena of lasers has expanded to include light-emitting diodes and other sources of light. Various wavelengths used are in the range of red and near infrared spectrum. Each wavelength has a unique interaction with the respective target tissues. High doses of laser have certain drawbacks and, in order to overcome these issues, widespread research is going on low-level laser therapy (LLLT). Low-level laser therapy results in direct biostimulation action on various cells of the body. It is reported that LLLT could enhance the process of wound healing and also has stimulating effects on bone cells and can hasten the repair process of the bone. In spite of many reports of affirmative findings from experiments conducted in vitro, in animal models, and in randomized controlled clinical trials, the effects of LLLT remain debatable. On the contrary, additional research still needs to be done in order to check the efficacy for periodontal treatment. This article focuses on the effects of LLLT on various tissues, its dosage, mechanisms of action, and applications in the field of dentistry.

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“…The RBC membrane can undergo large deformations and the cell shape is squeezed to a diameter of 3µm while flowing through the vessel. Deformed RBCs may increase blood viscosity and flow resistance, thus resulting in myocardial infarction and apoplexy (Mi et al, 2006). The circulation phenomenon can be aggravated under the presence of a pathological condition such as stenosis inside the microvessel, such as stenosis (Pozrikidis, 2003;Bagchi, 2007).…”

Section: Introductionmentioning

confidence: 99%

Numerical investigation on the structural characteristics of multiple RBCs in a stenotic microcapillary under plasma-alcohol solution

Cheema

Park

2015

Korea-Aust. Rheol. J.

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Alcohol significantly affects blood rheology and influences the mechanical behavior of red blood cells (RBCs). Previous studies indicate that plasma-RBC and multiple RBC interaction are important indicators for atherosclerosis progression. Therefore, multiphysics interactions under highly viscous conditions of alcohol consumption and stenosis structure must be investigated. A 2D microcapillary model, wherein multiple RBCs float through a stenotic structure, was established to investigate the effect of alcohol on cell motion and deformability under various flow conditions. Results show that the deformed cells inside the stenosis increase flow resistance and increase plasma velocity gradient in the pre and post stenotic regions. Moreover, the effect of the initial RBC position is important describing the RBC deformation pattern. The structural properties of RBCs may be significantly affected when the stenosis path is filled by cells that increase flow resistance.

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Effect of low power laser irradiation on disconnecting the membrane-attached hemoglobin from erythrocyte membrane

Cited by 26 publications

References 15 publications

Early micro-rheological consequences of single fraction total body low-dose photon irradiation in mice

Early micro-rheological consequences of single fraction total body low-dose photon irradiation in mice

Low-level Laser Therapy: A Literature Review

Numerical investigation on the structural characteristics of multiple RBCs in a stenotic microcapillary under plasma-alcohol solution

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