Effect of low-intensity eccentric resistance training with blood flow restriction on the activation and proliferation indicators of satellite cells

Blood Flow Restriction Training and Betaine Supplementation as a Novel Combined Modality to Augment Skeletal Muscle Adaptation: A Short Review

“…This effect may be in part mediated by neuronal nitric oxide released secondary to events of cellular membrane stretch (7). Human interventions using BFR training demonstrate increased Pax7 (required for maintenance and initial proliferation of satellite cells) and myogenic regulatory factor levels (transcription factors that regulate satellite cell proliferation and differentiation), including MyoD and Myf5 mRNA (39,57,60). Alternatively, other investigations have returned equivocal expression of myogenic markers between occluded and nonoccluded interventions (20,51).…”