“…Small molecule inhibitors have advantages over larger molecules, such as monoclonal antibodies. These advantages include easy diffusion across the cell membrane, which facilitates large-scale experiments in which there might be difficulties in transfection or knockdown using RNAi (Gowda, Jones, Banerjee, & Robertson, 2013; Madani, Naderi, Dissanayake, Tan, & Seifalian, 2011; Parhi, Mohanty, & Sahoo, 2012; Perumal, Banerjee, Das, Sen, & Mandal, 2011). Small molecule inhibitors can be administered orally, whereas biologics generally require injection or another parenteral administration.…”