2006
DOI: 10.1016/j.ijpharm.2005.10.002
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Effect of lipid-containing, positively charged nanoemulsions on skin hydration, elasticity and erythema—An in vivo study

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Cited by 154 publications
(81 citation statements)
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“…39,40 Moreover, changes in the SC could be attributed to the movement of aqueous fluid into the polar pathway, thus increasing the interlamellar volume of the lipid bilayer in the SC. 46 However, it is important to note that changes to the SC were minimized as the proportion of CP934 increased. This indicated that fewer droplets came out from NGs containing high proportions of CP934.…”
Section: Histological Investigation Of Skin Treated With Ne or Ngsmentioning
confidence: 99%
“…39,40 Moreover, changes in the SC could be attributed to the movement of aqueous fluid into the polar pathway, thus increasing the interlamellar volume of the lipid bilayer in the SC. 46 However, it is important to note that changes to the SC were minimized as the proportion of CP934 increased. This indicated that fewer droplets came out from NGs containing high proportions of CP934.…”
Section: Histological Investigation Of Skin Treated With Ne or Ngsmentioning
confidence: 99%
“…The alterations in surface resistance, of palmar skin in particular, are complex and comprise a combination of viscous shearing effects; absorption of water by the skin and capillary adhesion effects [10,[13][14][15]. In addition, the plasticizing effect of water on keratin causes the stratum corneum to become less stiff and more deformable therefore increasing the area of contact and therefore increasing friction [16][17][18]. Indeed, using a laboratory based model of blister formation, the authors have already demonstrated that greater skin hydration is associated with greater risk of foot blisters [11].…”
Section: Introductionmentioning
confidence: 99%
“…Skin hydration is altered by environmental humidity [19], perspiration and topical preparations [17,20,21]. For example, foot sweat which is unable to wick away from the skin surface causes the skin to become moist and thereby increases the risk of M A N U S C R I P T…”
Section: Introductionmentioning
confidence: 99%
“…However, hydrogenated lecithin has the drawback of being susceptible to oxidation and colour change and can also cause destabilization of anti-bacterial systems. As alternatives to lecithin, certain fatty ester compounds comprising fatty acids esterified with fatty alcohols have also been identified for making emulsions [11]. However, a systematic study using these kinds of emulsifiers for incorporating materials such as carotenoids (e.g.…”
Section: Introductionmentioning
confidence: 99%