Effect of lifestyle modification education based on health belief model in overweight/obese patients with non-alcoholic fatty liver disease: A parallel randomized controlled clinical trial

Nourian, Mojgan; Askari, Gholamreza; Golshiri, Parastoo; Miraghajani, Maryam; Shokri, Samira; Arab, Arman

doi:10.1016/j.clnesp.2020.04.004

Cited by 23 publications

(34 citation statements)

References 31 publications

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“…Furthermore, education plays an important role in the world of behavior. This is because the more knowledge a person gains in education, the more they will know what preventive measures must be taken to avoid fatal things such as health problems (Nourian et al, 2020). In this study, it was found that the highest education of workers was Senior High School education (45%).…”

Section: Discussionmentioning

confidence: 65%

The Relationship between Duration of Benzene Exposure with Liver Enzymes in Car Painting Workshop Workers

Yatulaini

Tualeka

Jalaludin

et al. 2021

IJOSH

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Introduction: Benzene is a carcinogenic compound that can be found in a car painting workshop in Surabaya. The source of benzene in the car painting workshop comes from thinners. Inhalation is the main route for benzene to enter the body. The duration of benzene exposure can affect the accumulation of benzene concentrations. If work safety is not considered, the benzene compound can cause the liver disease. Furthermore, SGOT and SGPT are basic parameters of liver function. The study aims to determine the relationship between the duration of benzene exposure with SGOT and SGPT levels in car painting workshop workers. Method: observational research with a cross-sectional approach was applied as the method of this study. The research was conducted in a car painting workshop in 2019 with 20 workers. The variables were the duration of benzene exposure (hours/day) and levels of SGOT and SGPT. Data analysis used the Fisher's Exact Test and Coefficient Contingency test. Results: Workers worked with a duration of benzene exposure ≤ 8 hours/day by 70% and > 8 hours/day by 30%. The measurement results exceeded the normal limit with the value of SGOT of 15% and the SGPT of 30%. Furthermore, the Sstatistical test show p-values between the duration of benzene exposure and SGOT (0.202) and SGPT (0.303), body weight with SGOT (1.000) and SGPT (1.000), education with SGOT (0.199) and SGPT (0.182) and alcohol consumption with SGOT (1.000) and SGPT (1.000). Conclusion: There was no relationship between the duration of benzene exposure with SGOT and SGPT levels in car painting workshop workers in Surabaya with a p-value >0.05.Keywords: car painting workers, duration of benzene exposure, SGOT, SGPT

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Section: Discussionmentioning

confidence: 65%

The Relationship between Duration of Benzene Exposure with Liver Enzymes in Car Painting Workshop Workers

Yatulaini

Tualeka

Jalaludin

et al. 2021

IJOSH

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“…Fourteen studies measured the effect of exercise alone on intrahepatic lipids, assessed by H-MRS [ 40 – 42 , 45 , 48 , 48 , 53 ], MRI [ 38 , 39 , 43 ], US [ 44 , 47 , 50 , 52 ] and Fibroscan CAP (46). Four studies researched the effect of diet alone measured by US [ 56 , 58 , 59 ] and MRI [ 57 ]. Six of eight studies assessing the effect of combined interventions evaluated IHL with H-MRS [ 24 , 64 ], NAS score [ 63 , 65 ], US [ 62 ] and liver-spleen ratio by computed tomography [ 66 ].…”

Section: Resultsmentioning

confidence: 99%

“…In diet alone interventions, Nourian et al [ 58 ] assessed the effect of enhancing the intake of fruits, vegetables, complex carbohydrates, white meat, and fish while avoiding unhealthy fats and refined carbohydrates. They compared that with usual care and showed that the severity of liver steatosis, evaluated with ultrasonography, improved significantly in the intervention group compared to the control group (p = 0.025).…”

Section: Resultsmentioning

confidence: 99%

Lifestyle changes in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis

et al. 2022

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Background Non-alcoholic fatty liver disease is a liver condition that is increasing worldwide and expected to become the number one cause of cirrhosis and hepatocellular carcinoma in the next 5 years. Currently there are no successful or approved pharmacological treatments. Weight loss is the first-line therapy as a 7 to 10% reduction improves steatosis, inflammation, hepatocyte ballooning, and fibrosis. To achieve this, lifestyle interventions including daily exercise and diet must be encouraged. We aimed to assess the effects of diet, exercise, or a combination of both compared to conventional treatment in patients with non-alcoholic fatty liver disease. Methods and finding A literature search was performed in CENTRAL, EMBASE, and PubMed. Randomized controlled trials comparing lifestyle changes with conventional treatment were included, without date restriction. Two authors searched studies according to eligibility criteria, extracted data, and assessed study quality. Subgroup analysis was made by type of intervention, duration of intervention and supervision. We calculated mean differences between the intervention and the control group with their corresponding 95% confidence intervals. Quality of the evidence was assessed using the Cochrane Risk of bias tool. This study is registered in PROSPERO, number CRD42020184241, and checked with the PRISMA checklist. 30 RCTs met the inclusion criteria. Compared to conventional treatment, combined exercise with diet seems to elicit greater reductions in ALT (MD: -13.27 CI 95% -21.39, -5.16), AST (MD: -7.02 CI 95% -11.26, -2.78) and HOMA-IR (MD: -2.07 CI 95% -2.61, -1.46) than diet (ALT MD: -4.48 CI 95% -1.01, -0.21; HOMA-IR MD: -0.61 CI 95% -1.01, -0.21) and exercise (ALT and AST non-significant; HOMA-IR MD = -0.46 CI 95% -0.8, -0.12) alone. Additionally, exercise improved quality of life, cardiorespiratory fitness, and weight (MD: -2.64 CI 95% -5.18, -0.09). Conclusion Lifestyle changes are effective in the treatment of NAFLD. Diet and exercise combined are superior to these interventions alone in improving liver enzymes and HOMA-IR.

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“…Existing trials in this area are limited, focusing primarily on patients on dialysis and on individual exercise [ 34 – 37 ]. CKD programs could benefit from the knowledge gained in proven, group-based programs used in prevention or management or other chronic conditions, where tools like goal setting, problem solving, responding to barriers and challenges, and building social support have been successfully used to improve health behaviors (for example [ 18 , 30 , 38 , 39 ]).…”

Section: Discussionmentioning

confidence: 99%

Perceptions of physical activity and technology enabled exercise interventions among people with advanced chronic kidney disease: a qualitative study

et al. 2021

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Background Exercise improves health outcomes and quality of life in persons with chronic kidney disease (CKD). The numbers of persons with advanced CKD meeting physical activity guidelines however is low. We undertook a qualitative study of men and women aged 36–74 from various race/ethnic populations with advanced CKD not requiring dialysis to describe their experiences and opinions around prior physical activity, motivating factors for and barriers to exercise, and perceptions of exercise-promoting technology and group-based programming designed to improve physical activity levels. Methods Nineteen persons with advanced CKD not requiring dialysis were interviewed at two high volume nephrology clinics enriched with racial/ethnic minority patients (Emory University and Santa Clara Valley Medical Center). We used thematic analysis to identify dominant themes (n = 4) and subthemes (n = 19) around exercise experience, barriers, motivators, views, and preferences. Results Four dominant themes and 19 subthemes were identified. The most common motivators to exercise included physical and mental health benefits, appearance, improvement in energy levels, and potential social interaction in group-based programs. Common barriers included health concerns, particularly complications related to other co-morbidities, as well as time and transportation constraints. Participants were skeptical of exercise programs solely reliant on technology. Conclusions The use of group-based exercise programs may motivate persons with CKD to increase exercise levels, while programs entirely based on technology may be less effective.

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Effect of lifestyle modification education based on health belief model in overweight/obese patients with non-alcoholic fatty liver disease: A parallel randomized controlled clinical trial

Cited by 23 publications

References 31 publications

The Relationship between Duration of Benzene Exposure with Liver Enzymes in Car Painting Workshop Workers

The Relationship between Duration of Benzene Exposure with Liver Enzymes in Car Painting Workshop Workers

Lifestyle changes in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis

Perceptions of physical activity and technology enabled exercise interventions among people with advanced chronic kidney disease: a qualitative study

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