Effect of left ventricular volume on results of coronary artery bypass grafting

Volume overload modulates effects of cardiac resynchronization therapy independently of myocardial reperfusion: results of the RESYNC study

“…Similar results have been observed in other categories of patients with a viable myocardium undergoing coronary revascularization or with valvular diseases undergoing surgery, in whom any benefit is limited by the degree of volume overload [23,24]. These data also confirm that ventricular enlargement and increase of end-diastolic and end-systolic volumes are important and independent contributors to prognosis, and that the use of these measures in the process of decision-making may be useful in candidates for CRT in whom resynchronization should be performed before severe left ventricular enlargement occurs.…”

Clinical Results of Coronary Revascularization in Left Ventricular Dysfunction

“…In addition, many other studies, including the present one, demonstrate improved LVEF, functional status, and quality of life, as well as decreased ventricular size, even in long-term follow-up, for patients treated with CABG, which implies reverse remodeling of the failing heart. 9,13,[16][17][18] …”

Does resting two-dimensional echocardiography identify patients with ischemic cardiomyopathy and low likelihood of functional recovery after coronary revascularization?

“…In a previous study by Yamaguchi et al [29], including 20 patients with LVEF < 30%, improvement in LVEF after revascularization was observed less frequently in patients with an ESVI index Z 100 ml/m 2 . Also in the study by Kim et al [30] the LVEF failed to improve after revascularization in patients with an ESVI index Z 100 ml/m 2 . Finally, in a recent study by our group, patients with enlarged volumes did not improve in LVEF after revascularization even in the presence of viable myocardium [31].…”