Effect of late percutaneous angioplastic recanalization of total coronary artery occlusion on left ventricular remodeling, ejection fraction, and regional wall motion

Improvement in Survival Following Successful Percutaneous Coronary Intervention of Coronary Chronic Total Occlusions: Variability by Target Vessel

“…There are also improvements in clinical outcomes such as reduced incidence of MI, reduced need for CABG, and significant reductions in angina burden after CTO PCI (7,23). Improvements in regional and global wall motion are evident on myocardial perfusion scintigraphy, echocardiography, and left ventriculography following PCI of CTO (18,24,25). Positive effects on left ventricular remodeling have been reported in patients undergoing cardiac magnetic resonance imaging up to 3 years after CTO PCI (26).…”

Changes in myocardial ischemic burden following percutaneous coronary intervention of chronic total occlusions

“…Other observational studies have suggested additional benefits, including improvements in survival [1][2][3][4][5] and left ventricular ejection fraction [16][17][18]. In the absence of definitive randomized clinical trial data, further studies are warranted to delineate any potential survival advantage associated with CTO PCI.…”

Prediction of Left Ventricular Function After Drug-Eluting Stent Implantation for Chronic Total Coronary Occlusions

“…However, the effect of PCI on myocardial contractility and left ventricular volumes of the individual patient with CTO is incompletely understood. Previous studies used left ventricular angiography to study left ventricular function and volumes after balloon angioplasty or bare-metal stents for CTO, but results have been equivocal (5)(6)(7). These equivocal results may partly be caused by the rather crude measurements offered by left ventricular angiography in conjunction with the high restenosis and reocclusion rate after balloon angioplasty or bare-metal stent implantation.…”