Effect of Laser Phototherapy on the Hyalinization Following Orthodontic Tooth Movement in Rats

Habib, Fernando; Gama, Sabrina Kívia Correia; Ramalho, Luciana Maria Pedreira; Cangussú, Maria Cristina Teixeira; Neto, Fernando Presídio dos Santos; Lacerda, Juliana Andrade de; Araújo, Telma Martins de; Pinheiro, António Luiz Barbosa

doi:10.1089/pho.2011.3085

Cited by 19 publications

(12 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These effects are due to its ability to stimulate cell metabolism, angiogenesis, bone formation and osteoclastogenesis (Garnero et al, 1994;Fassbender et al, 2009;Fujita et al, 2008.;Fujiyama et al, 2008;Habib et al, 2012;Genc et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Effect of Low Level Laser Therapy on Local Bone Resorption During Orthodontic Treatment: A Randomized Controlled Trial

Domínguez

León

Aristizabal

2016

Int. J. Odontostomat.

View full text Add to dashboard Cite

DOMINGUEZ, Á.; LEÓN, P.; ARISTIZABAL. J. F. Effect of low level laser therapy on local bone resorption during orthodontic treatment. A randomized controlled trial. Int. J. Odontostomat., 10(3):483-490, 2016. ABSTRACT:The aim of this study was to assess whether the application of low-level laser therapy (LLLT) during the first stage of orthodontic treatment has an effect on local bone resorption and is detectable at the systemic level by measuring deoxypyridinoline levels (Pyrilinks) in urine. This was a randomized (1:1), double-blind, active-controlled, parallel-group trial. 28 adult patients who were going to start orthodontic treatment were randomly divided into the control group (n: 13) and the experimental group (n: 15), the latter of which received LLLT. All of the subjects underwent testing of urine samples: the first one on the day before the beginning of orthodontic treatment (T0), and the second one 5 days after bracket placement to measure Pyrilinks values (Dpd/Cr) in urine. Group differences were evaluated with Student's paired t-test. At the beginning of the study, the Pyrilinks were in the normal range for 53.57 % of the patients, and 46.43 % had elevated values according to the normal ranges. Only taking into account the normal values at (T0), the average Pyrilinks for control group (T0) were 5.75± 1.20 nM/mM, (T1): 6.02±3.00 nM/mM. For experimental group, (T0) was 5.71± 0.72, and it was 6.63± 0.73 in (T1).There were no significant differences in the Pyrilinks changes. (p= 0.75). In the experimental group levels raised statistically significant (p = 0.009). LLLT on patients starting orthodontic treatment with normal Pyrilinks levels have a statistically significant increment on their levels 5 days post irradiation.

show abstract

Section: Introductionmentioning

confidence: 99%

Effect of Low Level Laser Therapy on Local Bone Resorption During Orthodontic Treatment: A Randomized Controlled Trial

Domínguez

León

Aristizabal

2016

Int. J. Odontostomat.

View full text Add to dashboard Cite

show abstract

“…Bone formation acceleration is one of the various biostimulating effects of low level lasers 1 . Laser efficiency in bone healing has been confirmed in various researches [7][8][9] and there's also been reference to accelerating bone neoformation in midpalatal expansion cases 1, [10][11] . Laser irradiation could potentially stimulate the recruitment of osteoblasts and/or their maturation throughout the bone edges of the midpalatal suture in expansion 1 .…”

Section: Introductionmentioning

confidence: 86%

LED phototherapy on midpalatal suture after rapid maxilla expansion: a Raman spectroscopic study

Rosa

Habib

Araújo

et al. 2015

Mechanisms for Low-Light Therapy X

Self Cite

View full text Add to dashboard Cite

A quick bone formation after maxillary expansion would reduce treatment timeand the biomodulating effects of LED light could contribute for it. The aim of this study was to analyze the effect of LED phototherapy on the acceleration of bone formation at the midpalatal suture after maxilla expansion. Thirty rats divided into 6 groups were used on the study at 2 time points -7 days: Control; Expansion; and Expansion + LED; and 14 days: Expansion; Expansion + LED in the first week; Expansion and LED in the first and second weeks. LED irradiation occurred at every 48 h during 2 weeks. Expansion was accomplished using a spatula and maintained with a triple helicoid of 0.020" stainless steel orthodontic wire. A LED light (λ850 ± 10nm, 150mW ± 10mW, spot of 0.5cm 2 , t=120 sec, SAEF of 18J/cm 2 ) was applied in one point in the midpalatal suture immediately behind the upper incisors. Near infrared Raman spectroscopic analysis of the suture region was carried and data submitted to statistical analyzes (p≤0.05). Raman spectrum analysis demonstrated that irradiation increased hydroxyapatite in the midpalatal suture after expansion. The results of this indicate that LED irradiation; have a positive biomodulation contributing to the acceleration of bone formation in the midpalatal suture after expansion procedure.

show abstract

“…1,3,4,5,[7][8][9][10][11][12][14][15][16][17][18]20,[23][24][25][26] We describe four fundamental points for experimental models to ensure that the evaluation of the effects of medication and phototherapy on induced tooth movement and associated root resorption is free of external influence.…”

Section: Palavras-chavementioning

confidence: 99%

Effects of medications and laser on induced tooth movement and associated root resorption: four key points

Consolaro

2013

Dental Press J. Orthod.

View full text Add to dashboard Cite

The following four fundamental points on the use of experimental models will be described to ensure an accurate evaluation of the effects of medication and laser therapy on induced tooth movement and associated root resorption: (1) If the objective is to check the effect on root resorption, the forces experimentally applied must produce a lesion on the cementoblast layer in all specimens; (2) If the objective is to optimize induced tooth movement and reduce treatment time without side effects, the forces experimentally applied should not produce a lesion in the cementoblast layer in any specimen; (3) The laser therapy operator, the person administering medication and the person that places appliances should not know which animals will effectively receive the test treatment, and the control groups should receive placebo treatments; (4) CT and microscopic analysis of the specimens should be random, and the group to which the specimen belongs should not be identified to ensure that the person reading images and the pathologists are not influenced in their evaluation of phenomena. These measures will ensure that results are more reliable and easier to extrapolate to orthodontic clinical practice.

show abstract

Effect of Laser Phototherapy on the Hyalinization Following Orthodontic Tooth Movement in Rats

Abstract: It is possible to conclude that the use of laser light caused histologic alterations during the orthodontic movement characterized by increased formation of areas of hyalinization at early stages, and late reduction when compared to nonirradiated animals.

Cited by 19 publications

References 41 publications

Effect of Low Level Laser Therapy on Local Bone Resorption During Orthodontic Treatment: A Randomized Controlled Trial

Effect of Low Level Laser Therapy on Local Bone Resorption During Orthodontic Treatment: A Randomized Controlled Trial

LED phototherapy on midpalatal suture after rapid maxilla expansion: a Raman spectroscopic study

Effects of medications and laser on induced tooth movement and associated root resorption: four key points

Contact Info

Product

Resources

About