Effect of Lamivudine Treatment in the Third Trimester in Hepatitis B Positive Pregnant Women in Decreasing the Viral Load and Subsequent Foetal Transmission
Abstract:BACKGROUND Hepatitis B infection is most commonly acquired through perinatal or horizontal transmission. The combined immunity of hepatitis B vaccine and high-titre hepatitis B immunoglobulin HBIG has excellent efficacies in blocking the maternal-foetal transmission of hepatitis B virus. This study was aimed to stop such transmission from mothers with high hepatitis B virus DNA viral loads by giving them lamivudine antenatally. The aim of the study is to study the effect of lamivudine treatment to decrease hep… Show more
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