Effect of Isotretinoin Oral on Acne Vulgaris (A Review of Systematic and Metaanalysis Studies on Alanine Aminotransferase Levels, Aspartate Aminotransferase, Lipid Profile, Homeostatic Model Assessment for Insulin Resistance, Complete Blood Count, Fasting Blood Glucose)
Abstract:Background: Oral isotretinoin is known to has a large role in the treatment of acne vulgaris, but unfortunately has signicant side effects.
Observation of laboratory changes during oral isotretinoin intake is important in order to ensure safety. Medline Pubmed, Scopus, Methods:
ProQuest, Cochrane library, ClinicalTrials.gov, the reference list, conference proceedings, researchers in eld of eligible studies were searched.
Result: 17 studies (1573 patients) were included into meta-analysis. Mean difference val… Show more
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