Effect of intratonsillar injection of steroids on the palatine tonsils of rabbits

Cho, Do‐Yeon; Sinha, S.; Gardner, James M.; Schaller, Michael P; Pamnani, Ravinder D.; Felt, Stephen A.; Barral, Joëlle K.; Messner, Anna H.

doi:10.1002/lary.24396

Cited by 1 publication

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“…However, as the focus of the study was the association between ATH and SCD, and considering the difficulty of a detailed assessment in children in this age group, we only observed the degree of nasal obstruction caused by the pharyngeal and palatine tonsils. It is possible that the use of topical and systemic corticosteroids may transiently affect the degree of nasal obstruction and, even, the tonsillar dimensions, 23 24 although this hypothesis has been refuted by some authors. 25 …”

Section: Discussionmentioning

confidence: 99%

Adenotonsillar Hypertrophy in Pre-School Children with Sickle Cell Disease and Diagnostic Accuracy of the Sleep Disturbance Scale for Children

Góis

D’Ávila

Cipolotti

et al. 2017

Int Arch Otorhinolaryngol

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Introduction Adenotonsillar hypertrophy is more common in children with sickle cell disease, and can lead to sleep-disordered breathing. Objectives To determine the frequency of adenotonsillar hypertrophy in pre-school children with sickle cell disease and assess the diagnostic accuracy of the sleep-disordered breathing subscale in the Sleep Disturbance Scale for Children. Method Observational study with a group of 48 children with sickle cell disease and a control group of 35 children without the disease. The children underwent oropharingoscopy and video nasal endoscopy. The parents and/or guardians answered the questions of the subscale. Results Adenotonsillar hypertrophy was observed in 25% of the children in the study group, and in 20% of the children in the control group, with no statistical difference between the groups. The subscale score ranged from 3 to 11 in both groups. There was a statistical significance in the study group. The average was 4.79 (standard deviation [SD] ± 2.50), with 4.19 (SD ± 1.72) among the children without adenotonsillar hypertrophy, and 6.5 (SD ± 3.40) among the children with adenotonsillar hypertrophy. There was also a statistical significance in the control group. The average was 5.23 (SD ± 2.81), with 4.44 (SD ± 2.2) among the children without adenotonsillar hypertrophy, and 7.87 (SD ± 2.89) among the children with adenotonsillar hypertrophy. Conclusion Adenotonsillar hypertrophy was not associated with sickle cell disease in pre-school children. The subscale of sleep-disordered breathing in the Sleep Disturbance Scale for Children was a useful tool for the diagnostic suspicion of adenotonsillar hypertrophy in children in this age group.

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Section: Discussionmentioning

confidence: 99%