Effect of intense pulsed light treatment on human skin<i>in vitro</i>: analysis of immediate effects on dermal papillae and hair follicle stem cells

Larouche, Danielle; Kim, Dong Hyun; Ratté, Gilles; Beaumont, Clément; Germain, Lucie

doi:10.1111/bjd.12477

Cited by 6 publications

(5 citation statements)

References 45 publications

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“…Bulge stem cells are located relatively far from the hair matrix compared with dermal papillae. Larouche et al also reported damage caused by heat extended over the dermal papilla cells, whereas stem cells were mostly spared after IPL hair removal [35].…”

Section: Discussionmentioning

confidence: 98%

Nonpigmented hair removal using photodynamic therapy in animal model

et al. 2016

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Section: Discussionmentioning

confidence: 98%

Nonpigmented hair removal using photodynamic therapy in animal model

et al. 2016

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“…Lasers with various wavelengths or IPL are now considered the gold standard treatment for many cutaneous vascular anomalies [ 19 ]. These techniques are based on the selective absorption of a brief radiation pulse that generates and confines heat at certain pigment targets and are also good and safe methods to reduce the number and size of hairs [ 20 ]. Though vascular lasers proved to be fairly effective, the high cost for devices and maintenance is an obstacle in real practice, whereas RF is inexpensive, is easy to handle, and needs little maintenance.…”

Section: Discussionmentioning

confidence: 99%

27.12 MHz Radiofrequency Ablation for Benign Cutaneous Lesions

Kim

Hyun

Piquette³

et al. 2016

BioMed Research International

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As surgical and/or ablative modalities, radiofrequency (RF) has been known to produce good clinical outcomes in dermatology. Recently, 27.12 MHz RF has been introduced and has several advantages over conventional 4 or 6 MHz in terms of the precise ablation and lesser pain perception. We aimed to evaluate the clinical efficacy and safety of 27.12 MHz RF for the treatment of benign cutaneous lesions. Twenty female patient subjects were enrolled. Digital photography and a USB microscope camera were used to monitor the clinical results before one session of treatment with 27.12 MHz RF and after 1 and 3 weeks. Treated lesions included telangiectasias, cherry and spider angiomas, skin tags, seborrheic keratoses, lentigo, milium, dilated pore, acne, piercing hole, and one case of neurofibroma. For vascular lesions, clinical results were excellent for 33.3%, good for 44.4%, moderate for 11.1%, and poor for 11.1%. For nonvascular lesions (epidermal lesions and other benign cutaneous lesions), clinical results were excellent for 48.3%, good for 45.2%, moderate for 3.2%, and poor for 3.2%. No serious adverse events were observed. Mild adverse events reported were slight erythema, scale, and crust. The 27.12 MHz RF treatment of benign vascular and nonvascular lesions appears safe and effective after 3 weeks of follow-up.

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“…Histological analysis confirmed that the melanin-rich matrix cells of the bulb in anagen follicles and the hair shaft are principally targeted by IPL treatment, while white hairs and epidermis remained unaffected. Damage caused by heat sometimes extended over the dermal papilla cells, while stem cells were mostly spared [49]. Collateral damage does not deplete stem cells.…”

Section: In Vitro Effects Of Ipl On Fibroblasts Cytokines Etcmentioning

confidence: 99%

Intense Pulsed Light Therapy

Gu¹,

Liu²,

Liu³

2017

Photomedicine - Advances in Clinical Practice

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Intense pulsed light (IPL) is one of the most effective nonablative approaches to treat skin photoaging. The broad range of wavelengths (500-1200 nm) emitted from IPL devices effectively target both melanin and hemoglobin in the skin. Numerous trials show the effectiveness and compatibility of IPL devices in a variety of skin conditions, especially in cosmetic indications such as hypertrichosis and telangiectasias. Compared with the wide clinical use of IPL, the biochemical and molecular mechanism is not clear. Both in vivo and in vitro studies demonstrate that IPL could increase the production of extracellular matrix, promote the proliferation of fibroblasts, and increase the secretion of TGF-β and matrix metalloproteinases, which play important roles in the photorejuvenation effects of IPL. However, investigations regarding the detailed underlying mechanism are necessary.

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Effect of intense pulsed light treatment on human skinin vitro: analysis of immediate effects on dermal papillae and hair follicle stem cells

Cited by 6 publications

References 45 publications

Nonpigmented hair removal using photodynamic therapy in animal model

Nonpigmented hair removal using photodynamic therapy in animal model

27.12 MHz Radiofrequency Ablation for Benign Cutaneous Lesions

Intense Pulsed Light Therapy

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