Effect of insulin and glucose on the glucose consumption and glycogen synthesis by the rat diaphragm

Glucose metabolism in insulin administered euthyroid, hypothyroid and hyperthyroid rats.

“…These findings suggest glycogenesis or glycogenolysis is intimately related to the state of thyroid function even in rats with normal pancreatic function. These results are inconsistent with the work of Guardabassi et al (1963) and Snedecor (1972) (Abramova et al, 1974). Thus it is expected that when the hyperfunctioning state of the pancreas or the experimental hyperinsulin state is associated with hypothyroidism, the process of glycogenesis will be enhanced markedly.…”