Effect of in ovo ghrelin administration on hatching results and post-hatching performance of broiler chickens

Lotfi, Alireza; Shahryar, Habib Aghdam; Kaiya, Hiroyuki

doi:10.1016/j.livsci.2013.03.020

Cited by 22 publications

(21 citation statements)

References 43 publications

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“…Pre-experimental tests showed that administration of acetic acid (as a solvent) injection did not have any biological effects on animals' health, performance and related parameters (14). Ghrelin was administered peripherally (I.P.…”

Section: Methodsmentioning

confidence: 99%

“…In total, preproghrelin coding sequences have been identified in 31 species of birds such as chicken, emu, turkey, goose, duck, pigeon and Japanese quail (20). The impacts of ghrelin on growth performance of chickens and goose have been studied in numerous experiments (2,13,14). However, it has been documented that ghrelin has GH-releasing activity in vertebrates such as chicken, it might also cause particular and different functions such as feed intake inhibition in birds (9).…”

Section: Introductionmentioning

confidence: 99%

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Effects of peripheral ghrelin on growth performance, selected blood biochemical parameters and thyroid hormone in Japanese quail (Coturnix coturnix japonica)

Shahryar¹,

Habib²,

Lotfi³

et al. 2018

Ankara Üniversitesi Veteriner Fakültesi Dergisi

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Summary:The aim of present study was to investigate the effects of peripheral administration of ghrelin on performance and some serum parameters of Japanese quail. One hundred twenty 21 day-old male Japanese quails were divided into three groups for a 35 days experimental rearing period. The control group (G0) included no injection as an intact, the second group (treatment 1/G50) received 50 ng ghrelin/kg body weight (BW), and the third group (treatment 2/G100) was given 100 ng ghrelin/kg BW. Ghrelin was administrated (I. P. administration) at the onset of the experimental rearing period on 21-day old birds. Blood samples were taken at two different times: 1) 12 hrs after the injection, and; 2) at the end of the rearing period (on day 35). The effects of ghrelin were evaluated during experimental rearing periods. There were no changes in feed intake and body weight gain (BWG) following ghrelin administration at different dosages (50 or 100 ng/ kg BW), whereas a minor decrease in feed intake was observed in G100 group. Feed conversion ratio (FCR) is significantly decreased in G50 and G100, compared to control (P<0.05). Thyroxin (T4) was increased in ghrelin-administered groups in both samples (short/long-term). In conclusion, ghrelin administration in Japanese quails may improve FCR, and stimulate secretion of thyroid hormones, without severe effects on feed intake. However, it did not have considerable effects on carcass characteristics and serum biochemical measures in short and long-terms in Japanese quails.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of peripheral ghrelin on growth performance, selected blood biochemical parameters and thyroid hormone in Japanese quail (Coturnix coturnix japonica)

Shahryar¹,

Habib²,

Lotfi³

et al. 2018

Ankara Üniversitesi Veteriner Fakültesi Dergisi

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“…Pre-experimental tests showed that injecting acetic acid (as a solvent) did not have any biological effect on performance and the related parameters (Lotfi et al, 2013). Ghrelin was injected (IP: intraperitoneal) at the onset of the experimental rearing phase (28-day-old birds).…”

Section: Injection Proceduresmentioning

confidence: 99%

“…Ghrelin has been identified in six species of birds including chicken, emu, turkey, goose, duck and Japanese quail (Kaiya et al, 2008). A possible impact of ghrelin on chickens' growth was studied in Lotfi et al (2011Lotfi et al ( , 2013. Although it has been demonstrated that ghrelin has a growth-hormonereleasing activity in mammalian and non-mammalian vertebrates, like chickens, it might also cause particular physiological functions such as food intake inhibition in birds .…”

Section: Introductionmentioning

confidence: 99%

The effect of peripheral administration of ghrelin on the performance of growing geese

Shahryar

Lotfi

2015

Arch. Anim. Breed.

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Abstract. The purpose of the present study is to investigate the effect of intraperitoneal (IP) injection of ghrelin on goose performance. Hence, forty-eight 28-day-old geese were assigned into three treatments which lasted 40 days. The first intact group included no injection; that is, treatment 1 was characterized by G0; treatment 2, given to the second intact group, was characterized by G50, 50 ng kg −1 ghrelin body weight (BW); and treatment 3, given to the third intact group, was characterized by G100, 100 ng kg −1 ghrelin BW. Ghrelin was injected at the outset of the experimental rearing period (28-day-old birds). Blood samples were taken at two different times: (1) 12 h after the injection and (2) at the end of the rearing period. The effects of the injections were examined and evaluated during two rearing periods (28-48 days old and 48-68 days old). In the second treatment (G50), ghrelin injection caused an increase in the feed intake during the growing period but not the finishing period. Body weight gain and feed conversion ratio (FCR) of the growing period and finishing period did not change following any ghrelin treatments (P > 0.05). Injection of ghrelin at G100 increased breast muscle (pectoral) weight. The results of the present study indicate that ghrelin has a significant impact on feeding regulation and muscle growth at a certain period in geese. Nevertheless, it should be noted that ghrelin may have different effects on feeding of avian species.

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“…Therefore, the study of regulation of growth hormone in poultry is considered to be a research gap. Hence, in recent years, studies on endocrine regulation of growth in poultry have focused on growth hormone (GH)-releasing peptides such as ghrelin (Kaiya et al, 2007(Kaiya et al, , 2008; Lotfi et al, 2013). The GHS-R 1 α transcripts have been identified in peripheral organs of chicken.…”

Section: Introductionmentioning

confidence: 99%

Effects of peripheral administration of ghrelin antagonist [D-Lys<sup>3</sup>]-GHRP-6 on growth performance and blood biochemical indices in broiler chickens

Shahryar

Lotfi

2016

Arch. Anim. Breed.

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Abstract. In the present study, possible effects of peripheral administration of ghrelin antagonist [D-Lys 3 ]-GHRP-6 on chicken performance, thyroid hormones level and serum biochemical parameters were investigated. Broiler chicks divided into five experimental groups were reared up to day 42. On day 21, a treatment was assigned to the five groups: group 1 (control), chickens without any administration of peptide or solution; group 2 (G50), chickens with intraperitoneal (IP) injection of 50 ng per 100 g body weight (BW) of D-Lys 3 peptide on day 21; group 3 (G100), chickens with IP injection of 100 ng per 100 g BW of D-Lys 3 peptide on day 21; group 4 (G150), chickens with IP injection of 150 ng per 100 g BW of D-Lys 3 peptide on day 21; and group 5 (G200), chickens with IP injection of 200 ng per 100 g BW of D-Lys 3 peptide on day 21. On days 21 (post-injection) and 42 (post-rearing), blood samples were obtained from the animals for laboratory analyses. Experimental groups administered the GHS-R antagonist showed less feed intake -i.e., administration of greater doses led to less feed intake (P < 0.01). Daily weight gains within groups G150 and G200 decreased (P < 0.01) in comparison with the control. The feed conversion ratio (FCR) did not differ among the groups. There was a significant difference between control and experimental groups for glucose, total cholesterol and phosphorus levels (P < 0.01) in postinjection samples. In post-injection and post-rearing blood samples, the thyroid hormone (T 3 and T 4 ) in 6 h increased in treated groups in comparison with the control (P < 0.01). The infusion of ghrelin antagonist [DLys 3 ]-GHRP-6 reduces feed intake and body weight. With regard to increase in T 4 level, it can be inferred that [D-Lys 3 ]-GHRP-6 may increase metabolic rate, lipolysis and weight loss, which is similar to results obtained in mammalian species.

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Effect of in ovo ghrelin administration on hatching results and post-hatching performance of broiler chickens

Cited by 22 publications

References 43 publications

Effects of peripheral ghrelin on growth performance, selected blood biochemical parameters and thyroid hormone in Japanese quail (Coturnix coturnix japonica)

Effects of peripheral ghrelin on growth performance, selected blood biochemical parameters and thyroid hormone in Japanese quail (Coturnix coturnix japonica)

The effect of peripheral administration of ghrelin on the performance of growing geese

Effects of peripheral administration of ghrelin antagonist [D-Lys<sup>3</sup>]-GHRP-6 on growth performance and blood biochemical indices in broiler chickens

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Effect of in ovo ghrelin administration on hatching results and post-hatching performance of broiler chickens

Cited by 22 publications

References 43 publications

Effects of peripheral ghrelin on growth performance, selected blood biochemical parameters and thyroid hormone in Japanese quail (Coturnix coturnix japonica)

Effects of peripheral ghrelin on growth performance, selected blood biochemical parameters and thyroid hormone in Japanese quail (Coturnix coturnix japonica)

The effect of peripheral administration of ghrelin on the performance of growing geese

Effects of peripheral administration of ghrelin antagonist [D-Lys&lt;sup&gt;3&lt;/sup&gt;]-GHRP-6 on growth performance and blood biochemical indices in broiler chickens

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Effects of peripheral administration of ghrelin antagonist [D-Lys<sup>3</sup>]-GHRP-6 on growth performance and blood biochemical indices in broiler chickens