Effect of impulse control disorders on disability and quality of life in Parkinson’s disease patients

Phu, Amy; Xu, Zheyu; Brakoulias, Vlasios; Mahant, Neil; Fung, Victor S.C.; Moore, Gregory R.; Starčević, Vladan; Martin, Andrew

doi:10.1016/j.jocn.2013.02.032

Cited by 78 publications

(72 citation statements)

References 28 publications

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“…Furthermore, according to the presence or absence of confounding factors -depression and Daytime sleepiness, fatigue can be divided into "primary" and "secondary" fatigue [23]. The significant relationship of features of DDS to worse QoL found in our study is supported by some studies which also found a significant link in this regard [27,28]. Impulsive and compulsive behaviors in PD are most commonly linked to dopaminergic drugs, especially dopamine agonists, but also L-dopa, and their prevalence in treated PD patients has been estimated around 14% [29].…”

Section: Discussionsupporting

confidence: 80%

Relationship between the non-motor items of the MDS–UPDRS and Quality of Life in patients with Parkinson's disease

Škorvánek¹,

Rosenberger²,

Minár³

et al. 2015

Journal of the Neurological Sciences

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Section: Discussionsupporting

confidence: 80%

Relationship between the non-motor items of the MDS–UPDRS and Quality of Life in patients with Parkinson's disease

Škorvánek¹,

Rosenberger²,

Minár³

et al. 2015

Journal of the Neurological Sciences

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“…In the present study, the finding of standard linear regression model found that severity of frontal behavioral changes was closely associated with the poor HRQoL of people with PD, which are consistent with previous findings showing that behavioral disturbances such as apathy and impulsivity negatively affect HRQoL in PD patients [9,10] . Together, these findings suggest that frontal behavioral changes are common and associated with the HRQoL of PD patients.…”

Section: Discussionsupporting

confidence: 93%

Impact of Frontal Lobe Function and Behavioral Changes on Health-Related Quality of Life in Patients with Parkinson's Disease: A Cross-Sectional Study from Southwest China

Guo

Song²,

Chen³

et al. 2015

Eur Neurol

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Background: Cognitive impairment may negatively impact the health-related quality of life (HRQoL) in patients with Parkinson's disease (PD). However, information on the effects of frontal lobe function and behavior changes on the HRQoL of the Chinese PD population is limited. Studies on the associations among frontal lobe function, behavioral changes and the HRQoL may help optimize the treatment and improve the HRQoL of PD patients. Methods: A total of 309 PD patients were evaluated using the Frontal Assessment Battery, the Frontal Behavioral Inventory (FBI) and the PD Questionnaire 39-item version (PDQ-39). Results: Patients with worse frontal lobe function were older (p < 0.001), had longer disease durations (p = 0.002), higher Unified Parkinson's Disease Rating Scale part III (UPDRS-III) scores (p < 0.001) and higher Hoehn and Yahr (H-Y) stages (p = 0.001), and exhibited significantly higher PDQ-39 summary index (SI; p = 0.001) compared with those who had better frontal lobe function. In addition, the disease duration (p = 0.008), UPDRS-III scores (p < 0.001), H-Y stage (p < 0.001), PDQ-39 SI and scores for each domain of the PDQ-39 (p < 0.001) were higher as the severity of frontal behavioral changes increased. The total FBI score (p < 0.001) was positively correlated with the PDQ-39 SI. Conclusions: Frontal behavioral changes were closely associated with poor HRQoL in Chinese PD patients.

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“…This added stressor multiplies the complexity of living with PD and has been found to have a significant detrimental effect on people's quality of life (Phu et al, 2014). Although ICDs are commonly under reported (Vilas, Pont-Sunyer, & Tolosa, 2011), it is estimated that between 10 and 14% of people with PD have ICDs (Giladi et al, 2007;Poletti et al, 2013;Weintraub, Potenza, Siderowf, & Voon, 2010), compared to between 1 and 8% within the general population (Dell'Osso, Altamura, Allen, Marazziti, & Hollander, 2006).…”

Section: Introductionmentioning

confidence: 99%

Impulse control disorders in Parkinson’s disease: Predominant role of psychological determinants

Garlovsky

Simpson

Grünewald

et al. 2016

Psychology & Health

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Objectives: Impulse Control Disorders (ICDs) in Parkinson's disease (PD) have previously almost exclusively been considered to result from anti-parkinsonian medication. However, this biomedical perspective has failed to achieve a full understanding of the phenomenon and it is argued that a failure to consider psychological factors is a critical omission. Design: The present study examined the predictive relationship between ICDs in PD and a range of

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Effect of impulse control disorders on disability and quality of life in Parkinson’s disease patients

Cited by 78 publications

References 28 publications

Relationship between the non-motor items of the MDS–UPDRS and Quality of Life in patients with Parkinson's disease

Relationship between the non-motor items of the MDS–UPDRS and Quality of Life in patients with Parkinson's disease

Impact of Frontal Lobe Function and Behavioral Changes on Health-Related Quality of Life in Patients with Parkinson's Disease: A Cross-Sectional Study from Southwest China

Impulse control disorders in Parkinson’s disease: Predominant role of psychological determinants

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