Effect of<i>Lithothamnium</i>sp and calcium supplements in strain- and infection-induced bone resorption

Taddei, Silvana Rodrigues de Albuquerque; Madeira, Mila Fernandes Moreira; Lima, Izabella Lucas de Abreu; Queiroz-Junior, Celso Martins; Moura, Adriana Pedrosa; Oliveira, Dauro Douglas; Andrade, Ildeu; Souza, Danielle da Glória de; Teixeira, Mauro Martins; Silva, Tarcı́lia Aparecida

doi:10.2319/080313-579.1

Cited by 8 publications

(7 citation statements)

References 23 publications

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“…With the methodology used, 15 publications about the role of calcium in periodontal disease were selected, specifically 12 observational studies in humans [20,21,22,23,24,25,26,27,28,29] and five experimental studies in animals [30,31,32,33,34]. Dietary intake estimates were obtained in nine of them [20,21,22,23,24,25,26,28,29].…”

Section: Resultsmentioning

confidence: 99%

“…Animal research was represented by three articles (Table 2), two performed in rats ( Rattus norvegicu s) [30,31] and one in mice ( Mus musculus ) [34]. Most of them analyzed the effect of dietary calcium deficiencies on alveolar bone [30,31], namely three considering interactions with pregnancy and lactation [30,31].…”

Section: Resultsmentioning

confidence: 99%

“…After 60 days, the number of osteoclasts was reduced in mice fed on diet rich in caclium, which led to diminished infection-induced alveolar bone loss. In addition, calcium-treated mice also presented decreased levels of tumor necrosis factor-α (TNF-α) in periodontal tissues ( p < 0.05) [34].…”

Section: Resultsmentioning

confidence: 99%

“…Experimental studies in rodents have been carried out especially in physiological situations with high requirements of Ca, namely in pregnancy [31,33] and lactation [30], but in all cases dietary Ca amount positively influenced alveolar bone. Anyway, the effects of a Ca-rich diet on the periodontium was tested in a periodontitis mice model induced by bacterial inoculation directly affecting bone metabolism, including ABL and osteoclast number, it also led to a lower of TNF-α [34], which also suggests an interesting role in inflammation regulation for this mineral in this tissue. The role of dietary phosphorus or magnesium has also been investigated but this only seems relevant when their amounts are very different respect than calcium.…”

Section: Discussionmentioning

confidence: 99%

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A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease

et al. 2016

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Abstract:Periodontal disease is an inflammatory disease with high prevalence in adults that leads to destruction of the teeth-supporting tissues. Periodontal therapy has been traditionally directed at reduction of the bacterial load to a level that encourages health-promoting bacteria and maintenance of oral-hygiene. The role of nutrition in different chronic inflammatory diseases has been the subject of an increasing body of research in the last decades. In this sense, there has been an important increase in the volume of research on role of nutrition in periodontitis since the diet has known effects on the immune system and inflammatory cascades. Minerals play a key role in all these processes due to the multiple pathways where they participate. To clarify the role of the different minerals in the establishment, progression and/or treatment of this pathology, a systemically review of published literature cited in PubMed until May 2016 was conducted, which included research on the relationship of these elements with the onset and progression of periodontal disease. Among all the minerals, calcium dietary intake seems important to maintain alveolar bone. Likewise, dietary proportions of minerals that may influence its metabolism also can be relevant. Lastly, some observations suggest that all those minerals with roles in immune and/or antioxidant systems should be considered in future research.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease

et al. 2016

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“…Recent evidence demonstrated that some nutritional regimens directly influence alveolar bone parameters in experimental models of periodontitis [11][12][13], orthodontic tooth movement [14], and bone repair after tooth extraction [15]. In particular, it was demonstrated that diet (in its different meanings of macro-and micronutrients) can affect the healing of the alveolus after tooth extraction, influencing both the morphology and the quality of alveolar bone [15].…”

Section: Introductionmentioning

confidence: 99%

Do Dietary Supplements and Nutraceuticals Have Effects on Dental Implant Osseointegration? A Scoping Review

et al. 2020

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Several factors affect dental implant osseointegration, including surgical issues, bone quality and quantity, and host-related factors, such as patients’ nutritional status. Many micronutrients might play a key role in dental implant osseointegration by influencing some alveolar bone parameters, such as healing of the alveolus after tooth extraction. This scoping review aims to summarize the role of dietary supplements in optimizing osseointegration after implant insertion surgery. A technical expert panel (TEP) of 11 medical specialists with expertise in oral surgery, bone metabolism, nutrition, and orthopedic surgery performed the review following the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) model. The TEP identified micronutrients from the “European Union (EU) Register of nutrition and health claims made on foods” that have a relationship with bone and tooth health, and planned a PubMed search, selecting micronutrients previously identified as MeSH (Medical Subject Headings) terms and adding to each of them the words “dental implants” and “osseointegration”. The TEP identified 19 studies concerning vitamin D, magnesium, resveratrol, vitamin C, a mixture of calcium, magnesium, zinc, and vitamin D, and synthetic bone mineral. However, several micronutrients are non-authorized by the “EU Register on nutrition and health claims” for improving bone and/or tooth health. Our scoping review suggests a limited role of nutraceuticals in promoting osseointegration of dental implants, although, in some cases, such as for vitamin D deficiency, there is a clear link among their deficit, reduced osseointegration, and early implant failure, thus requiring an adequate supplementation.

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Oral supplementation with Lithothamnion extract in horses subjected to oligofructose overload intake: effects on systemic inflammation and multiple organ function

Cota

Spadeto

Oliveira

et al. 2022

Journal of Equine Veterinary Science

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Effect ofLithothamniumsp and calcium supplements in strain- and infection-induced bone resorption

Abstract: These results indicate that the LTT supplement influences ABR, probably due to its calcium content, by affecting osteoclast function and local inflammatory response, thus modulating OTM and PD.

Cited by 8 publications

References 23 publications

A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease

A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease

Do Dietary Supplements and Nutraceuticals Have Effects on Dental Implant Osseointegration? A Scoping Review

Oral supplementation with Lithothamnion extract in horses subjected to oligofructose overload intake: effects on systemic inflammation and multiple organ function

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