2016
DOI: 10.1007/s40292-016-0130-y
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Effect of hypovolemia on efficacy of reflex maintenance of blood pressure on orthostatic challenge

Abstract: Maintenance of blood pressure after orthostatic challenge is not compromised after mild hypovolemia produced by donation of 450 ml of blood. However, mild hypovolemia results in increase in latency of response and is accompanied with larger magnitude of fall in blood pressure during orthostatic challenge.

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Cited by 3 publications
(2 citation statements)
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“…The BPV was analysed in the time domain to calculate SDNN, CoV (coefficient of variance) and RMSSD (square root of the mean of the sum of the squares of differences between adjacent BP readings). Similarly, for spectral analysis, the PSD was calculated using FFT by a Hanning window in the LF (0.04‐0.15 Hz) and HF (0.15‐0.40 Hz) bands, along with the total power …”
Section: Methodsmentioning
confidence: 99%
“…The BPV was analysed in the time domain to calculate SDNN, CoV (coefficient of variance) and RMSSD (square root of the mean of the sum of the squares of differences between adjacent BP readings). Similarly, for spectral analysis, the PSD was calculated using FFT by a Hanning window in the LF (0.04‐0.15 Hz) and HF (0.15‐0.40 Hz) bands, along with the total power …”
Section: Methodsmentioning
confidence: 99%
“…The pathogenesis of VVS is complex and includes, but is not limited to, hypovolemia ( 2 4 ), enhanced sympathetic nerve activity ( 5 , 6 ) and catecholamine levels ( 7 ), and excessive peripheral vasodilation ( 8 ). It was found that during an attack of VVS, the orthostatic stress, which was the major trigger, may initially stagnate blood in the veins of lower extremities due to gravitational forces ( 9 ) and thereby reduced the circulating blood volume, which activated an aberrant autonomic regulation ( 10 ), resulting in bradycardia ( 11 , 12 ) and/or hypotension, and ultimately decreasing the cerebral blood flow ( 13 15 ) and oxygen saturation ( 15 , 16 ). The relative central hypovolemia can be the initial factor that promotes the whole process.…”
Section: Introductionmentioning
confidence: 99%