2004
DOI: 10.1385/ncc:1:2:171
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Effect of Hypothermia on Serum Electrolyte, Inflammation, Coagulation, and Nutritional Parameters in Patients With Severe Traumatic Brain Injury

Abstract: Hypothermia of 33 degrees for 48-72 hours does not appear to increase the risk for coagulopathy and infections, although hypothermic patients exhibited significant increments in inflammatory markers such as C-reactive protein and white blood counts after rewarming.

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Cited by 37 publications
(39 citation statements)
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“…However, there were no significant differences in blood glucose level or insulin requirements in patients subjected to hypothermia (Clark et al, 2009;Tokutomi et al, 2004). Diuresis during hypothermia is due to increased venous return caused by vasoconstriction, leading to atrial natriuretic peptide activation and a decrease in the level of antidiuretic hormone (Giraud et al, 2013).…”
Section: Other Complicationsmentioning
confidence: 92%
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“…However, there were no significant differences in blood glucose level or insulin requirements in patients subjected to hypothermia (Clark et al, 2009;Tokutomi et al, 2004). Diuresis during hypothermia is due to increased venous return caused by vasoconstriction, leading to atrial natriuretic peptide activation and a decrease in the level of antidiuretic hormone (Giraud et al, 2013).…”
Section: Other Complicationsmentioning
confidence: 92%
“…Given that saline at higher temperatures can cause damage to red blood cells or coagulation factors, the saline-to-blood temperature gradient was significantly lower during rewarming than cooling (13°C vs. 31°C) (Dae et al, 2003). Slow rewarming is also advised because potassium levels decline during cooling, and the reverse can occur if rewarming occurs too rapidly (Tokutomi et al, 2004).…”
Section: Rewarming Speedmentioning
confidence: 99%
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“…However, therapeutic hypothermia does not appear to affect serum sodium levels (Tokutomi and Miyagi, 2004).…”
Section: Why Do Electrolytes Shift During the Induction Of Hypothermia?mentioning
confidence: 95%