“…Although hyperbaric oxygen therapy has primarily been directed toward wound healing, it has also been used to manage carbon monoxide poisoning (Myers et al, 1981) and anaerobic infection (Weinstein and Barza, 1976). Many of the wound healing studies have been involved with the effect of hyperbaric oxygen in the treatment of osteoradionecrosis (Greenwood and Gilchrist, 1973, Mansfield et al, 1981, Marx, 1983, Marx et al, 1985, osteomyelitis (Morrey et al, 1979, Kerley et al, 1981, Triplett et al, 1982 and burns (Korn et al, 1977, Niccole et al, 1977. These studies demonstrated HBO enhancement of fibroblastic activity, angiogenesis and neovascularization in "compromised" tissue, to ultimately promote healing.…”