Effect of hemodialysis on pulmonary function tests and plasma endothelin levels

Safa, Javid; Noshad, Hamid; Ansarin, Khalil; Nikzad, Alireza; Saleh, Parviz; Ranjbar, Abdolmohammad

doi:10.4103/1319-2442.135003

Cited by 4 publications

(4 citation statements)

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“…According to previous findings weight affects the normal respiratory pressures values as compared to other anthropometric parameters. (28) Among male gender FEV1, FVC and FEV1/FVC have significant correlation (P< 0.05) with age and weight while no significant correlation (P> 0.05) with height and BMI. VC and PEF do not show any significant correlation with age, weight, height and BMI among male gender.…”

Section: Discussionmentioning

confidence: 86%

Reference Values for Respiratory Parameters in General Adult Population

Ilyas,

Tariq,

Batool

et al. 2023

PJMHS

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Background: Reference values for maximum inspiratory pressure are varied among different studies and this variability is generalized by demographic differences and test performance measurement. Objective: To acquire a comprehensive set of Reference values for respiratory pressures in a general adult population and to evaluate possible associations with sex, age and body mass index (BMI). Methods: The study design was cross-sectional and sample was drawn through simple random sampling technique. The sample size was calculated using 584 based on parent article, divided on gender 292 participants each. Inclusion criteria was age between 18-40, both genders, Healthy people and moderately active. Exclusion criteria were Signs of ischemia/infarction, Stenosis or insufficiency of the cardiac valve, Systolic and diastolic failures. Data was collected from Sialkot, Pakistan. Basic anthropometric values for age, height, weight and BMI were measured. Spirometry values for FVC, FEV1, FEV1/FVC, VC, and PEF were measured. Descriptive measures were in the form of mean and standard deviation was calculated through SPSS version 25. Pearson Correlation between variables was also found. Results: Among male gender PEF have significant correlation (P< 0.00) with age while BMI have no significant correlation. FVC, FEV1, FEV1/FVC, VC do not show any significant correlation with age, weight, height and BMI among male gender. Among female gender PEF showed significant correlation (P< 0.00) with age only. FVC, FEV1, FEV1/FVC, VC do not show any significant correlation with age, weight, height and BMI among female gender. Clinical Significance: this research provided the knowledge about basic respiratory parameters and its correlation with anthropometric measurements. It can help develop the basis for occurrence of respiratory disturbances in long term due to deviation from normal parameters. Conclusion: Among males age, gender, height weight and BMI doesn’t affect normative values for respiratory pressure. While among females’ normative values of respiratory pressures are only affected by age. Keywords: Respiratory Pressure, Adult, Population, Reference values.

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Section: Discussionmentioning

confidence: 86%

Reference Values for Respiratory Parameters in General Adult Population

Ilyas,

Tariq,

Batool

et al. 2023

PJMHS

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“…But several investigators reported that these values significantly improved in post dialysis period than pre dialysis period in those patients who received 6 months maintenance hemodialysis. [22][23][24] In this study,all patients had abnormal lung functions before dialysis. In addition, 34(85%) and 23(57.5%) patients had both restrictive and obstructive disorders before and after hemodialysis session respectively.…”

Section: Discussionmentioning

confidence: 95%

“…Several investigators have suggested different mechanisms for pulmonary involvement in this specific group of patients. [23][24][25] Research evidence has shown that decrement of ventilatory variables in CKD stage-V patients may be due to pulmonary oedema, pulmonary fibrosis and calcification, pleural effusion, intravascular and interstitial volume overload, pulmonary hypertension, decrease respiratory muscle strength, anemia, uremic toxins, electrolyte disorders and/or acid base imbalance. 10,18 These abnormalities have been demonstrated to improve or resolve after hemodialysis.…”

Section: Discussionmentioning

confidence: 99%

Acute effect of hemodialysis on FVC, FEV1 and FEV1/FVC% in chronic kidney disease stage- V patients

Guha Roy,

Begum,

Akhter Mukta

2024

J Bangladesh Soc Physiol

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Background: Chronic kidney disease (CKD) stage-V is associated with impairment of pulmonary functions which may be improved by taking hemodialysis treatment. Objective: To observe the acute effect of hemodialysis on FVC,FEV1 and FEV1/FVC in CKD stage-V patients. Methods: This prospective observational study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from September 2015 to August 2016 on 40 male newly diagnosedCKD stage-V patients aged 30-55years who were advised to take maintenance hemodialysis. Forty age and BMI matched apparently healthy male were control. FVC, FEV1 and FEV1/FVC%were assessed by portable digital spirometer. before and after their first hemodialysis session in patients and once in healthy control. For statistical analysis, paired and independent sample‘t’ tests were done, as applicable. Results:Percentage of predicted values of FVC and FEV1 were found significantly lower in patients than the healthy control at baseline but FEV1/FVC%was almost similar to control. Again, FVC, FEV1 and FEV1/FVC were found significantly increased after the end of hemodialysis than the before hemodialysis session. Conclusion:The pulmonary functions were reduced in newly diagnosed CKD stage-V patients and hemodialysis cause immediate improvement of lung functions in patients with CKD stage-V. J Bangladesh Soc Physiol 2022;17(2): 85-90

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“…Pulmonary disorders like pulmonary edema, pleural effusion, acute respiratory distress syndrome, increased pulmonary capillary permeability, pulmonary fibrosis, pulmonary calcification, pulmonary hypertension, hemosiderosis, pleural fibrosis, obstructive apnea, muscle myopathy, and low respiratory muscle strength are observed among these patients (10)(11)(12)(13). They might be directly due to uremic toxins or indirectly because of anemia, immune suppression, extra calcification, malnutrition, electrolyte disorders, acid-base imbalance, and volume over-load (9,(14)(15)(16)(17)(18)(19).…”

Section: Introductionmentioning

confidence: 99%

Early Effects of Hemodialysis on Pulmonary Function in Patients with End-Stage Renal Disease

Momeni

Shahraki

Yarmohammadi

et al. 2020

Zahedan J Res Med Sci

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Background: Renal failure may directly or indirectly influence pulmonary ventilation. Since hemodialysis can decrease the extra liquids, improvement in pulmonary function by decreasing liquids in the lungs is expected. Objectives: This study aimed to assess the effects of acute hemodialysis on spirometry parameters. Methods: A cross-sectional study was conducted among patients with end-stage renal disease who referred for hemodialysis to Ali Ibn Abitaleb Hospital of Zahedan City during 2016. Patient data including age, gender, and body mass index (BMI) were collected. Spirometry was performed one hour before and after hemodialysis, and spirometry parameters including vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC, peak expiratory flow (PEF), forced expiratory flow between 25% and 75% FVC (FEF 25% - 75%) were measured. Results: A total number of 50 patients (30 men) completed spirometry. In men, there were a significant increase in FEV1 (mean difference = 0.217; P = 0.003) and FVC (0.298; P = 0.027) and a significant decrease in FEV1/FVC (-4.153; P = 0.038) after hemodialysis. In women, there was no significant change in the means of spirometry parameters. In addition, no significant relationship was found between PFT changes and BMI, weight change, or ultrafiltration volume. Conclusions: Our results showed that hemodialysis may improve pulmonary function tests in men. Studies with larger cohorts of patients are needed to derive valid effect estimates of hemodialysis on spirometry parameters with considering the role of chronic kidney diseases, various underlying diseases, different hemodialysis methods, and other related confounders.

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Effect of hemodialysis on pulmonary function tests and plasma endothelin levels

Cited by 4 publications

References 0 publications

Reference Values for Respiratory Parameters in General Adult Population

Reference Values for Respiratory Parameters in General Adult Population

Acute effect of hemodialysis on FVC, FEV1 and FEV1/FVC% in chronic kidney disease stage- V patients

Early Effects of Hemodialysis on Pulmonary Function in Patients with End-Stage Renal Disease

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