Effect of heat stress on blood rheology in different pigs breeds

Waltz, Xavier; Baillot, Michelle; Connes, Philippe; Gourdine, Jean-Luc; Philibert, Lucien; Beltan, Eric; Chalabi, Tawfik; Renaudeau, David

doi:10.3233/ch-131722

Cited by 6 publications

(7 citation statements)

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“…In this experiment, three different pig breeds with assumed different heat stress tolerance were studied: Large White (little tolerance), Creole (good tolerance) and a cross between Large White and Creole breeds. Although red blood cell deformability was higher in Creole pigs exposed to heat stress compared to Large White pigs, the hematological and hemorheological responses to heat stress were very similar [5] . However, in this previous study, the physiological, hematological and hemorheological parameters were measured after 5 days of heat stress exposure and pigs were probably acclimatized at that time.…”

Section: Introductionmentioning

confidence: 85%

“…In practice, pigs were restrained on their back by two handlers while a third experimenter took blood samples. To avoid excessive stress on the animal, this procedure never exceeded 2 minutes [5] .…”

Section: Methodsmentioning

confidence: 99%

“…Blood rheology is a key factor of blood flow and cardiovascular functioning [3] , [4] and hemorheological changes under heat stress could interfere with the physiological thermoregulatory adaptations [5] . We recently investigated the effect of heat stress on physiological, hematological, hemorheological parameters in different pig breeds [5] . In this experiment, three different pig breeds with assumed different heat stress tolerance were studied: Large White (little tolerance), Creole (good tolerance) and a cross between Large White and Creole breeds.…”

Section: Introductionmentioning

confidence: 99%

“…We hypothesized that short-term physiological adaptation to heat stress could be accompanied by hematological and hemorheological changes. In addition, we hypothesized that the lack of changes in hematological and hemorheological parameters occurring after 5 days of heat stress exposure [5] could be explained by the changes in water consumption occurring immediately after the beginning of heat stress exposure. Therefore, water restriction should affect hematological and hemorheological changes and physiological acclimation during heat stress exposure.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Hydration Level and Heat Stress on Thermoregulatory Responses, Hematological and Blood Rheological Properties in Growing Pigs

et al. 2014

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Heat stress is one of the major limiting factors of production efficiency in the swine industry. The aims of the present study were 1) to observe if hemorheological and hematological parameters could be associated to physiological acclimation during the first days of heat stress exposure and 2) to determine if water restriction could modulate the effect of thermal heat stress on physiological, hematological and hemorheological parameters. Twelve Large White male pigs were divided into an ad libitum and a water restricted group. All pigs were submitted to one week at 24°C (D-7 to D-1). Then, at D0, temperature was progressively increased until 32°C and maintained during one week (D1 to D7). We performed daily measurements of water and feed intake. Physiological (i.e., skin temperature, rectal temperature, respiratory rate), hematological and hemorheological parameters were measured on D-6, D-5, D0, D1, D2 and D7. Water restriction had no effect on physiological, hematological and hemorheological parameters. The first days of heat stress caused an increase in the three physiological parameters followed by a reduction of these parameters suggesting a successful acclimation of pigs to heat stress. We showed an increase in hematocrit, red blood cell aggregation and red blood cell aggregation strength during heat stress. Further, we observed an important release of reticulocytes, an increase of red blood cell deformability and a reduction of feed intake and blood viscosity under heat stress. This study suggests that physiological acute adaptation to heat stress is accompanied by large hematological and hemorheological changes.

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Section: Introductionmentioning

confidence: 85%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effects of Hydration Level and Heat Stress on Thermoregulatory Responses, Hematological and Blood Rheological Properties in Growing Pigs

et al. 2014

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“…In biomedical research, minipigs are established animal models for vascular surgery and interventions [2,[10][11][12][13]. However, only few systematic data on characteristics of the morphology of blood vessels are available, which would allow study planning and refinement according to the 3R principles of Russel and Burch [14].…”

Section: Introductionmentioning

confidence: 99%

Positioning of minipigs and its bearing on cervical vessels

Niehues

Müller

Hünigen

et al. 2016

JCB

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In this study, diameter and length of cervical vessels in minipigs of different ages were examined with respect to either prone or supine positioning. In addition, age related changes were established, since scanning of vessels was carried out at different stages of growth. Due to their early maturity, minipigs are used frequently as animal models for surgery or vascular interventions. To gain open access to cervical vessels the animals have to be in supine position. Since this does not correspond to a physiological position, changes in vessel length and inner diameter were measured. The results were compared to vessel length and diameter in the prone position, which represents the physiological position. Contrast enhanced computed tomography (CT) was used for examination, which allowed for describing these changes in vivo without compromising the physiological pressure and condition. Significant changes could not be observed in the arterial system. However, the venous system showed significant changes (p < 0.05) in both vessel diameter and length. Moreover, results showed that development of the cervical vascular system is completed, when the minipigs are 17 months old.

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