Effect of Gold Modification with 3-Mercaptopropionic Acid, Cysteamine and Gold Nanoparticles on Monoethanolamine Electrooxidation

Abstract

In this work, a gold electrode modified with selfassembled layers (SAMs) composed of 3-mercaptopropionic acid, cysteamine and gold nanoparticles was prepared. The electrode with SAMs endowed with gold nanoparticles gave the high catalytic effect for monoethanolamine (MEA) electrooxidation in solution at pH 7. For this novel sensor, a linear relationship between the current response of MEA at the potential of peak maximum (j p ) and the concentration of this compound in solution (c MEA ) was found, over the range 0.1 μM to 0.8 M with the detection sensitivity equal to about 5 A cm −2 mol −1 dm 3 (at v=0.1 V s −1 ) and the detection limit of 0.046 μM.

Sensitivity Enhancement of Electrochemical Biosensor for Point of Care (POC) Applications: Vi Antigen Detection as a Case Study

“…The -COOH groups of 3-MPA (pKa = 4.34 ± 0.20) are mostly dissociated at pH = 7 of the electrolytes 47 and negatively charged COO -terminated layer preferably interacts with a positively charged amine group of EDC-NHS as shown in Fig. 8.…”