Effect of general anesthesia and minor surgical trauma on urine and serum measurements in horses

Watson, Zara; Steffey, Eugene; VanHoogmoed, Linda M.; Snyder, Jack R.

doi:10.2460/ajvr.2002.63.1061

Cited by 27 publications

(9 citation statements)

References 12 publications

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“…An increase in serum phosphate after induction of anaesthesia as seen in both groups in the present study has been reported earlier [ 47 - 49 ]. Johnson et al [ 47 ] and Lindsay et al [ 48 ] speculated that this phosphate derived from dephosphorylation of CP and ATP, since these were the most likely sources of phosphate.…”

Section: Discussionsupporting

confidence: 91%

Metabolism before, during and after anaesthesia in colic and healthy horses

2007

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Background: Many colic horses are compromised due to the disease state and from hours of starvation and sometimes long trailer rides. This could influence their muscle energy reserves and affect the horses' ability to recover. The principal aim was to follow metabolic parameter before, during, and up to 7 days after anaesthesia in healthy horses and in horses undergoing abdominal surgery due to colic.

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Section: Discussionsupporting

confidence: 91%

Metabolism before, during and after anaesthesia in colic and healthy horses

2007

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“…Increasing dietary protein and potassium will also increase urine volume; feeding a legume diet can result in a 3–4 times increase in urine flow over diets of Timothy hay or wheat straw . Experimentally baseline flow rates are reported in the range of 0.92–1.24 mL/kg/h, but most of these animals had been maintained on high protein, high potassium legume diets . Tasker () reported a flow rate of 0.52 mL/kg/h in horses on a mixture of Timothy and alfalfa hay .…”

Section: Discussionmentioning

confidence: 99%

Systemic, Renal, and Colonic Effects of Intravenous and Enteral Rehydration in Horses

Lester

Merritt

Kuck

et al. 2013

Veterinary Internal Medicne

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Background: Intravenous (IV) and intragastric (IG) administration of fluid therapy are commonly used in equine practice, but there are limited data on the systemic, renal, and enteric effects.Hypothesis: IV fluid administration will increase intestinal and fecal hydration in a rate-dependent manner after hypertonic dehydration, but will be associated with significant urinary water and electrolyte loss. Equivalent volumes of IG plain water will result in comparatively greater intestinal hydration with less renal loss.Animals: Six Thoroughbred geldings. Methods: Experimental study. 6 by 6 Latin square design investigating constant rate IV administration at 50, 100, and 150 mL/kg/d over 24 hours in horses dehydrated by water deprivation. Equivalent volumes of IG plain water were administered by 4 bolus doses over 24 hours.Results: Water deprivation resulted in a significant decrease in the percentage of fecal water, and increases in serum and urine osmolality. IV fluids administered at 100 and 150 mL/kg/d restored fecal hydration, but increasing the rate from 100 to 150 mL/kg/d did not confer any additional intestinal benefit, but did result in significantly greater urine production and sodium loss. Equivalent 24-hour volumes of plain water resulted in greater intestinal water and less urine output.Conclusions and Clinical Importance: IV polyionic isotonic fluids can be used to hydrate intestinal contents in situations where enteral fluids are impractical. IV fluids administered at three times maintenance are no more efficacious and might be associated with adverse physiological findings after withdrawal. Bolus dosing of IG water can be used to restore intestinal water with minimal adverse effects.

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“…16 Also, the increase in urine flow must be considered when making decisions regarding anesthetic management. 17 To our knowledge, there are no published reports on the diuretic effects of medetomidine and xylazine in cats. Given the differences among species, it is important to examine diuretic effects of both drugs in cats.…”

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confidence: 98%