Effect of Gas-Permeable Contact Lenses on the Endothelium of Corneal Transplants

Speaker, Mark G.; Cohen, Elisabeth J.; Edelhauser, Henry F.; Clemons, Carol S.; Arentsen, Juan J.; Laibson, Peter R.; Raskin, Elsa M.

doi:10.1001/archopht.1991.01080120087032

Cited by 19 publications

(6 citation statements)

References 11 publications

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“…Cell counts of over 1000 cells/mm 2 are less risky but may still be susceptible, and problems may arise in stressful conditions, such as contact lens wear for correction of astigmatism. 17,18 Although this study was a retrospective review, it does provide long-term data (10-year follow-up) about the endothelial cell count, morphology, and corneal topography in keratoconus patients who have undergone PKP. These data can help surgeons inform their patients of the long-term prognosis of these grafts.…”

Section: Discussionmentioning

confidence: 99%

Penetrating Keratoplasty for Keratoconus

Zadok¹,

Schwarts²,

Marcovich³

et al. 2005

Cornea

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Section: Discussionmentioning

confidence: 99%

Penetrating Keratoplasty for Keratoconus

Zadok¹,

Schwarts²,

Marcovich³

et al. 2005

Cornea

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“…One main complication for inexperienced cataract surgeons is a decompensated transplant needing retransplantation. Cell counts of over 1000 cells/mm 2 are less risky, but may still be susceptible, and problems may arise in stressful conditions, such as contact lens wear for correction of astigmatism (Matsuda et al 1989, Speaker et al 1991.…”

Section: Discussionmentioning

confidence: 99%

Follow‐up study of human corneal endothelial cells, photographed in vivo before enucleation and 20 years later in grafts

Vasara

Setälä

Ruusuvaara

1999

Acta Ophthalmologica Scandinavica

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ABSTRACT.Purpose: To evaluate the long-term (20-year) survival of transplanted human corneal endothelial cells. Methods: The donor endothelium had been photographed 20 years ago with a specular microscope both before enucleation in the melanomatous eye and in situ after keratoplasty. The same donor endothelial cells were now photographed again 20 years later with a modern specular microscope to ascertain the morphology and cell density of the grafts. Results: In the earlier study the mean postoperative endothelial cell density was 1357∫543 cells/mm 2 , the average cell loss 11 months postoperatively being 48.2%; 20.5 years postoperatively the cell loss was 62.9% of the preoperative cell count. In our well-documented patient population the endothelial cell loss during the last 19 years had been only 14.7%, which amounts to a cell loss of less than 1% per year. Conclusion: In transplanted corneas, the main endothelial cell loss seems to take place during the first 1-2 postoperative years.

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“…Rigid gas-permeable (RGP) lenses, and silicone lenses have not been observed to induce changes in endothelial morphology (Schoessler et al 1984, Nieuwendaal et al 1991. Even endothelial cells of corneal transplants tolerate RGP lens wear well (Speaker et al 1991). Thus far, persons who have experienced long-term wear of solely RGP lenses are difficult to find.…”

Section: Discussionmentioning

confidence: 99%