Effect of Galohgor Cookies and Powder Drinks on Visceral Adipose Tissue and Lipid Profile in Patients with Type 2 Diabetes Mellitus

Abstract

This study aimed to assess the intervention effect of cookies and galohgor powder drinks on visceral adipose tissue (VAT) and lipid profile in patients with type 2 diabetes mellitus. The study design was quasi experimental. Subjects of this study were 26 adults with type 2 diabetes mellitus in Bogor District, West Java. Subjects were divided into two intervention groups; cookies and galohgor powder drinks (GCPD) group and cookies and powder drinks without galohgor (CPD) group. Both interventions were given for 38 days period. Analysis of Covariance (ANCOVA) was applied to assess the effect of interventions. The average changes in VAT controlled by covariates in GCPD group was significantly higher than in CPD group (-33.3% vs +6.7%; p<0.05), while the average changes in blood total cholesterol in GCPD group and CPD group were-8.5% and-3.8% (p>0.05). The average changes of triglycerides level in GCPD and with CPD group were-30.9% and +1.6% (p>0.05). The average changes in HDL level for GCPD group and CPD group were-9.0% and-12.0% (p>0.05). The average changes in LDL level for GCPD group and CPD group were-3.9% and-1.6% (p>0.05). Hence, it can be concluded that the administration of cookies and galohgor powder drinks significantly reduced the Visceral Adipose Tissue (VAT) in patients with type 2 diabetes mellitus.

The Galohgor Nutraceutical Cookies Effects on β-Carotene Serum and Oxidative Stress of Postpartum Mothers

“…In an animal study, Leatemia (2010) reported that galohgor significantly increases endogenous antioxidant superoxide dismutase (SOD) and reduces malondialdehyde (MDA) plasma. In another study examining type 2 diabetes mellitus patients, nutraceutical galohgor was shown to reduce visceral fat and oxidative stress biomarkers (Setyaningsih et al, 2017; Damayati et al, 2018). However, despite various studies that indicate the potential effect of galohgor on diabetes treatment, the effect of galohgor consumption on levels of oxidative stress in postpartum mothers has not been revealed.…”

Effect of Galohgor Cookies Intake by Postpartum Mother on Newborn’s Growth

“…IGF concentration significantly decreased in the control group, whereas it could be maintained in the intervention group during postpartum (Table 3). Galohgor has long been used by postpartum mothers in the Sundanese community 16 . Several studies have scientifically proven the benefits of galohgor for postpartum mothers 16,17 .…”

“…Galohgor has long been used by postpartum mothers in the Sundanese community 16 . Several studies have scientifically proven the benefits of galohgor for postpartum mothers 16,17 . This study supports those scientific evidences whereas Galohgor cookies appeared to be able to support the growth of newborns.…”

“…Galohgor is a native Sundanese herbal medicine made from 56 types of plants, including leaves, stems, fruits, nuts, herbs and spices, commonly consumed by postpartum mothers and rich in vitamin A and βcarotene [16][17][18] . Galohgor has been shown to accelerate uterine recovery and lactation time, and to increase milk production in experimental animals 16 . Genetically, βcarotene is believed to be responsible for galactogogic effect of Galohgor by enhancing the expression of the connexin (Cx43) and β-casein (Csn2) genes 17 .…”

“…Galohgor cookie is one of the developed products that commercially sold and has been tested on patients with type 2 diabetes mellitus. 16,18,21 . Our recent study showed that Galohgor cookies reduced oxidative stress in postpartum mothers 22 .…”