Effect of fruits of Opuntia elatior Mill on mast cell degranulation

Chauhan, Sanjay P; Sheth, Navin; Suhagia, Bhanubhai N.

doi:10.4103/0975-7406.148779

Cited by 6 publications

(5 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These observations are consistent with previous research showing that the size, shape and function of MCs vary according to tissue residency and microenvironment [8,20,78,79]. Because TB staining does not detect granules inside MCs after degranulation, some fully degranulated MCs may not be detected [80][81][82]. This LM limitation in the resolution of MCs may lead to confusion regarding the numbers and size of all MC populations present in tissues.…”

Section: Discussionsupporting

confidence: 90%

Mast Cells in the Milieu: A Comparative Study in the Tongue and Liver

Makeyeva,

Leach,

Ryugo

2023

Proc Shevchenko Sci Soc Med Sci

View full text Add to dashboard Cite

Mast Cells (MCs) have diverse roles in health and disease. These immune cells migrate in a tissue-specific manner to target sites where they can alert or amplify immune responses through exocytosis of their bioactive granules. Granule exocytosis can be triggered by both external immunological and non-immunological signals. Depending on the local milieu, MCs are highly heterogeneous cells with significant phenotypic plasticity and functional diversity. The aim of this study was to investigate differences in MC populations in the tongue and liver to advance the understanding of how organ-specific location may affect MC phenotypic variance and functions. MCs were investigated using light and electron microscopy in tissues obtained from rats housed in identical conditions. Connective tissue MCs were identified in both the tongue and liver and showed phenotypic differences in secretory activity and granule characteristics. These findings indicate that phenotypic variance depends on tissue location. This knowledge may help develop strategies for preventing or treating diseases.

show abstract

Section: Discussionsupporting

confidence: 90%

Mast Cells in the Milieu: A Comparative Study in the Tongue and Liver

Makeyeva,

Leach,

Ryugo

2023

Proc Shevchenko Sci Soc Med Sci

View full text Add to dashboard Cite

show abstract

“…The OFJ exhibited significantly (P<0.001) concentration dependent inhibition of mast cell degranulation. IC50 value of OFJ was found 12.24 and 18 µl/ml for immunological and nonimmunological induced mast cell degranulation, respectively [28].…”

Section: Mast Cell Stabilization Activitymentioning

confidence: 91%

Opuntia Elatior Mill.–its Phytochemistry and Pharmacological Properties-a Review

SHARADA¹,

Acharya²

2022

Int J Pharm Pharm Sci

View full text Add to dashboard Cite

Opuntia elatior Mill. (OE) (Family Cactaceae), commonly recognized as Red Prickly pear, is a plant of varied nutritional and medicinal benefits. The species has been scrutinized for the composition and wide array of pharmacological activities. This review is attempted with an aim to document the updated status of OE with respect to its phytochemistry and pharmacological actions. The data is collected from the extensive review of literatures from scientific articles, dissertations and books available on various web-based search engines such as Pub-med, Google-scholar and Science direct and few unpublished observations. The fruit is reported to be rich in carbohydrates, flavonoids, phenolics, betalains, vitamin C and minerals like calcium, magnesium, iron, zinc, copper, and potassium. Extract and the fruit as a whole are reported for anti-oxidant, hematinic, anti-leukemic, anti-diabetic, analgesic and anti-inflammatory, anti-fertility, broncho-dilatory, mast cell degranulation, radio-protective and anti-arthritic activities. It is reported to be safe for administration in a dose dependent manner. OE is a nutritionally and medicinally important drug with a wide range of traditional and pharmacological applications. There is a vast scope for research on the varied traditional claims of this drug. This review might help for the further research on the species.

show abstract

“…In this way, OFI is valued for contributing to a healthy diet and because it is rich in health-promoting substances [ 5 , 6 ]. Some medicinal properties of OFI include antioxidant, analgesic, anti-inflammatory, diuretic, anti-diabetic, anti-hypercholesterolaemic and anti-carcinogenic [ 3 , 4 , 5 , 9 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. These properties allow the prevention of hangovers, lipid oxidation–reduction, prevention of some types of cancer, and reduction of the risk of diabetes (type 2) and cardiovascular diseases, two of the most common causes of death worldwide [ 5 , 28 , 29 ].…”

Section: Introductionmentioning

confidence: 99%

Physicochemical, Nutritional, and Medicinal Properties of Opuntia ficus-indica (L.) Mill. and Its Main Agro-Industrial Use: A Review

Martins

Ribeiro

Almeida

2023

Plants

View full text Add to dashboard Cite

The cactus, Opuntia ficus-indica (L.) Mill. (OFI) belongs to the Cactaceae family, which contains about 130 genera and nearly 1600 species. This review aims to evaluate this plant from several perspectives, namely, botanic, physicochemical, nutritional, and medicinal properties, as well as agro-industrial use. The botanical aspects and morphological characteristics of OFI enable genetic variability, ecological adaptation, and broad geographic distribution. Due to its physicochemical and nutritional composition, it has several medicinal properties appropriate (or suitable) for several industries, such as pharmaceutical, food, and cosmetics. Its fruit, the prickly pear (PP), has potential agro-industrial expansion through the application of different conservation and transformation methods, making it possible to obtain a variety of products. The PP is a source of several nutrients and is an effective system to produce varied foods, which have several advantages from a nutritional, sensory, economic, and shelf-life point of view.

show abstract

Effect of fruits of Opuntia elatior Mill on mast cell degranulation

Cited by 6 publications

References 14 publications

Mast Cells in the Milieu: A Comparative Study in the Tongue and Liver

Mast Cells in the Milieu: A Comparative Study in the Tongue and Liver

Opuntia Elatior Mill.–its Phytochemistry and Pharmacological Properties-a Review

Physicochemical, Nutritional, and Medicinal Properties of Opuntia ficus-indica (L.) Mill. and Its Main Agro-Industrial Use: A Review

Contact Info

Product

Resources

About