Effect of fluoride varnish supplemented with sodium trimetaphosphate on enamel erosion and abrasion: An in situ/ex vivo study

Abstract

TMP significantly enhanced the effects of F on enamel wear after erosive challenges, followed or not by abrasion.

Anti-Erosive Effect of Solutions Containing Sodium Fluoride, Stannous Chloride, and Selected Film-Forming Polymers

“…This is an important factor to be considered in future research, due to the influence of the abrasive challenge having an effect on the durability of film-forming copolymers on tooth surfaces Scaramucci et al, 2015Scaramucci et al, , 2016. Nevertheless, a negative effect of the abrasion was not observed in two previous investigations, in which phosphate polymers were capable of showing anti-erosive properties under toothbrushing conditions [Moretto et al, 2013;Scaramucci et al, 2016]. Another point that is worth mentioning is the use of enamel and dentin from bovine instead of human teeth.…”

In vitro effect of low-fluoride toothpastes containing sodium trimetaphosphate on enamel erosion

“…7,8,20 However, there are limited reports on the association between phosphates and fluoride on the progression of dental caries and erosion. 19,[21][22][23]25,27 Confirming the study hypothesis, the use of a LFD containing 250 ppm F supplemented with TMP led to significantly lower enamel wear when compared to its counterpart without TMP. Moreover, the test dentifrices promoted significantly higher effect against erosion when compared to the positive control (1,425 ppm F).…”

“…This is of concern because the effect of the toothpastes seen in the present study could potentially be counteracted by abrasive challenges or other ingredients in the formulation. In this sense, it is noteworthy that while some studies assessing the effects of toothpastes on erosion provided a very similar trend of enamel wear after erosive challenges alone (erosion) or followed by abrasion by toothbrushing (erosive wear), differing only in the magnitude of the wear values obtained, 21,25,27 other investigations do not support such assumption. 35 Therefore, although the protocol used does not invalidate the results obtained, it also does not allow the validation of the efficacy of the toothpastes tested due to the lack of abrasion by toothbrushing.…”

“…Five indentations were done 100 mm apart using a Knoop diamond indenter (25 g, 10 s). After the 2 experimental periods, the nail varnish on the reference surfaces of each block was carefully removed with acetone-soaked cotton wool and enamel loss was determined in relation to the reference surface by profilometry (Surftest SJ 401; Mitutoyo American Corp.) 27 . The profilometric trace (length = 2 mm) included the reference surface (baseline) and the exposed surface.…”

“…Five readings were performed on each block at intervals of 0.5 mm and the average enamel loss was calculated (mm). 8,21,27 The vertical distance between the horizontal line drawn on the reference area and the horizontal line drawn on experimental area was defined as tooth wear by using a software coupled to the profilometer. The reproducibility was only considered as acceptable if equal or higher than 90%.…”