Effect of feed additive supplementation on bovine subclinical mastitis

Abstract

Bovine mastitis is an important commercial and sanitary cost in milk production. The prevention and treatment of this disease is essentially based on the use of antibiotics that have limited effectiveness and can negatively affect milk quality. The aim of this study was to evaluate the effectiveness of an alternative treatment based on a symbiotic in the control and prevention of subclinical mastitis (SCM), and in the improvement of the quality of milk produced on a dairy farm in north-central Algeria. The milk of 68 cows was collected and analysed by somatic cell count and bacteriological analysis. Three samples were taken at one-month intervals. The first sample was taken before the administration of a feed additive (SYMBIOVEBA®) to lactating dairy cows. Animals were divided into two groups to study the effects (curative and preventive) of the symbiotic. Each group was further divided into two subgroups, where one received the symbiotic and the other was the control. The prevalence of subclinical mastitis at this farm was 33.82%. Bacterial identification was performed using classical methods only on the group of cows with mastitis; a total of 13 bacterial species were isolated from the three samples. Staphylococci were dominant, with a frequency of 45%, followed by Enterobacteriaceae (40%). These rates were considerably lower in both subgroups, though treated cows showed 100% cure rate for both Staphylococci and Enterobacteriaceae. Individual somatic cell count (ISCC) was performed on all three samples and in both groups, and revealed a cure threshold (S) of 200,000 cells/mL, and a 100% cure rate for the SYMBIOVEBA®-treated cow subgroup compared to 62.5% for the control subgroup (P<0.05).

Sulfur Amino Acid Metabolism and the Role of Endogenous Cystathionine-γ-lyase/H2S in Holstein Cows with Clinical Mastitis

“…However, the generation of drug residues and the emergence of antibiotic-resistant pathogens have increased the difficulty and cost of CM treatment in mammals and pose continuous risks to human health and food safety [ 6 , 7 ]. Thus, it is becoming increasingly urgent to develop novel prevention and treatment methods and non-antibiotic-resistant medicines [ 8 ]. Previous studies have investigated vaccine development, searched for new therapeutic alternatives to antibiotics, and even explored the application of traditional Chinese medicine to veterinary medicine [ 9 ].…”

βeta-lactam and Tetracycline Antibiotic Residues in Cow Milk in the Constantine region, Algeria

“…Our results are also similar β-lactams are the oldest but still one of the most widely used groups of antibiotics (Ghidini et al, 2002). β-lactam antibiotics are the most often used antibacterial substances in lactating cows for the treatment of bacterial infections (Dračková et al, 2009), especially mastitis which is one of the most common pathologies in dairy farming (Mimoune et al, 2021b), the important commercial and sanitary cost in milk production (Lamari et al, 2021), the most important cause of economic losses in the modern dairy industry (Benić et al, 2018), mastitis as the most expensive disease affecting dairy cattle worldwide and, therefore, the single largest cause of antibiotic usage in dairy herds in parenteral and intra-mammary therapy (Reybroecka et al, 2010). Consequently, it is the most common type of residues detected in milk (Gustavsson et al, 2004), responsible for approximately 95% of all milk antibiotic contamination (Movassagh and Karam, 2011a),…”

Content of tryptophan and kynurenines in serum and milk of dairy cows with mastitis caused by Streptococcus spp.

“…This applies not only to TRP but also to most amino acids, except for glutamate and aspartate (Klein et al., 2013). Therefore, it is widely accepted that differences in milk and serum concentrations of amino acids reflect their extensive utilization by the mammary gland (Klein et al., 2013; Lamari et al., 2021; Mepham, 1982).…”