Effect of external counterpulsation on cardiac work following cardiac surgery: Implications of the mechanism responsible for clinical benefits

Shimizu, Tsuyoshi; Kyo, Shunei; Morizumi, Sei; Ando, Takashi; Gon, Shigeyoshi; Suematsu, Yoshihiro

doi:10.1016/j.jjcc.2011.08.005

Cited by 4 publications

(1 citation statement)

References 29 publications

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“…These results are mostly consistent with previous investigations. Shimizu et al 24 showed that ECP increases the venous return and cardiac output during ECP in addition to causing diastolic augmentation and systolic unloading. Meanwhile, our results further confirmed that ECP provides diastolic augmentation and systolic unloading through enhancing venous return by squeezing the venous system.…”

Section: Discussionmentioning

confidence: 99%

External Counterpulsation Reduces Beat-to-Beat Blood Pressure Variability When Augmenting Blood Pressure and Cerebral Blood Flow in Ischemic Stroke

et al. 2016

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Background and PurposeExternal counterpulsation (ECP) is a noninvasive method used to enhance cerebral perfusion by elevating the blood pressure in ischemic stroke. However, the response of the beat-to-beat blood pressure variability (BPV) in ischemic stroke patients during ECP remains unknown.MethodsWe enrolled recent ischemic stroke patients and healthy controls. Changes in the blood flow velocities in bilateral middle cerebral arteries and the continuous beat-to-beat blood pressure before, during, and after ECP were monitored. Power spectral analysis revealed that the BPV included oscillations at very low frequency (VLF; <0.04 Hz), low frequency (LF; 0.04–0.15 Hz), and high frequency (HF; 0.15–0.40 Hz), and the total power spectral density (TP; <0.40 Hz) and LF/HF ratio were calculated.ResultsWe found that ECP significantly increased the systolic and diastolic blood pressures in both stroke patients and controls. ECP decreased markedly the systolic and diastolic BPVs at VLF and LF and the TP, and the diastolic BPV at HF when compared with baseline. The decreases in diastolic and systolic BPV reached 37.56% and 23.20%, respectively, at VLF, 21.15% and 12.19% at LF, 8.76% and 16.59% at HF, and 31.92% and 23.62% for the total TP in stroke patients, which did not differ from those in healthy controls. The change in flow velocity on the contralateral side was positively correlated with the total TP systolic BPV change induced by ECP (r=0.312, p=0.035).ConclusionsECP reduces the beat-to-beat BPV when increasing the blood pressure and cerebral blood flow velocity in ischemic stroke patients. ECP might be able to improve the clinical outcome by decreasing the beat-to-beat BPV in stroke patients, and this should be explored further in future studies.

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Section: Discussionmentioning

confidence: 99%

External Counterpulsation Reduces Beat-to-Beat Blood Pressure Variability When Augmenting Blood Pressure and Cerebral Blood Flow in Ischemic Stroke

et al. 2016

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Novel external counterpulsation system, compact counterpulsation, was effective to treat severe ischemic heart failure: a case report

et al. 2014

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Compact counterpulsation (CP) is a novel external counterpulsation system. The preoperative clinical utility of compact CP therapy in patients has not been established. In the present report, we describe a case wherein compact CP therapy was successfully used to treat severe ischemic heart failure. A 70-year-old man was diagnosed with ischemic heart disease and mitral valve regurgitation at 61 years of age. Therefore, he underwent coronary artery bypass and mitral valve plasty. The patient's condition started to gradually deteriorate at 68 years of age, and he became progressively dependent on catecholamine support. Mitral valve regurgitation recurred, which caused worsening of heart function. Before a mitral valve replacement, the patient had been treated with compact CP therapy to improve heart function and general condition. The patient's clinical condition improved with compact CP therapy after only ten sessions; in addition, he could be weaned off catecholamine support. No adverse effects were observed, and therefore, he could complete the CP therapy as an outpatient. Mitral valve replacement was performed after a total of 44 sessions. The patient had an uneventful postoperative course and was discharged on the 18th postoperative day. Compact CP therapy was thus performed on our patient without any discomfort and appears to be an effective treatment for patients with severe ischemic heart failure.

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Hemodynamics of ventricular-arterial coupling under enhanced external counterpulsation: An optimized dual-source lumped parameter model

Liao,

Li,

Cao

et al. 2024

Computer Methods and Programs in Biomedicine

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Effect of external counterpulsation on cardiac work following cardiac surgery: Implications of the mechanism responsible for clinical benefits

Abstract: ECP increases venous return, cardiac output, and cardiac work in addition to diastolic augmentation and systolic unloading. These actions may play important roles in the clinical benefits of ECP therapy. Our data also suggest that ECP is beneficial for patients undergoing cardiac surgery.

Cited by 4 publications

References 29 publications

External Counterpulsation Reduces Beat-to-Beat Blood Pressure Variability When Augmenting Blood Pressure and Cerebral Blood Flow in Ischemic Stroke

External Counterpulsation Reduces Beat-to-Beat Blood Pressure Variability When Augmenting Blood Pressure and Cerebral Blood Flow in Ischemic Stroke

Novel external counterpulsation system, compact counterpulsation, was effective to treat severe ischemic heart failure: a case report

Hemodynamics of ventricular-arterial coupling under enhanced external counterpulsation: An optimized dual-source lumped parameter model

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