Effect of Electrolyte on the Surface and Thermodynamic Properties of Amphiphilic Penicillins

Thermodynamics of Association of Structurally Related Amphiphilic Penicillins

“…The self-association of penicillins G and V was examined by gel filtration chromatography (5), and NMR techniques have been used in a study of penicillin G (6) and cloxacillin (7). We have recently reported the influence of electrolyte on the mode of association, micellar properties, and intermicellar interactions of cloxacillin, dicloxacillin, and flucoxacillin (8) and also analyzed the influence of the molecular structure on the ideality of mixing in micelles formed in binary mixtures of these amphiphiles (9). 1 To whom correspondence should be addressed.…”

Thermoresponsive Micelles from Oligopeptide‐Grafted Cyclotriphosphazenes

“…However, optical methods could not be used for our trimers because they showed strong absorption in the UV/Vis region and also fluorescence in the UV region. We employed the surface tension method to measure the CMC of trimer 3, [11] which gave rise to a value of 0.11 mg L À1 .…”

Influence of SDS and two anionic hydrotropes on the micellized state of the triblock copolymer E71G7E71

“…The penicillins can be considered as hydrotropes or hydrotropic agents if we considered that the term comprises hydrophilic and hydrophobic moieties, with the hydrophobic moiety being typically too small to induce micelle formation [33], and that the hydrotrope molecules are assumed to aggregate by a stacking mechanism of the planar aromatic ring present in their chemical structure, as is the case for the two penicillins [33]. The two penicillins differ in one extra chlorine atom in the meta position with respect to the first on the aromatic benzene ring of dicloxacillin if compared to cloxacillin, which has been key in providing different psychochemical properties for the two hydrotropes [34][35][36]. Previous studies have shown that these penicillins aggregate in aqueous solution by stacking with a low aggregation number that can be detected as a discontinuity of the concentration dependence of the physicochemical properties of the solution: conductivity, sound velocity, light scattering, etc.…”