Effect of dual ion implantation of calcium and phosphorus on the properties of titanium

Effects of calcium ion‐implantation of titanium on bone cell function in vitro

“…56 Modification of Ti surfaces by ion-implantation has previously been reported to augment the formation of hydroxyapatite-like calcium phosphate on exposure to simulated body fluid. 29,[57][58][59] In addition, our previous findings established that a Caand P-rich particulate deposit is also formed after brief immersion of the Ca-Ti, but not the Ti (control) discs in culture medium, 15 possibly also contributing to the MG-63 cell responses to the Ca-Ti surface shown here.…”

Ion implantation of titanium based biomaterials

“…Dual Ca and P ion implantation is a gradual development in this area of HA research and several groups [8,[68][69][70] have studied this aspect. In these methods, both Ca and P ions are incorporated into Ti surface.…”

“…Aside from the individual Ca or P implantation, Ti surface was modified to contain both Ca and P ions [69]. Under both short-term and long-term exposure conditions polarization resistance and corrosion potential of implanted Ti are higher than those of non-implanted Ti, to suggest the benefits of this treatment.…”

Zn/Ag micro-galvanic couples formed on titanium and osseointegration effects in the presence of S. aureus

“…The proper surface structural and compositional changes caused by bombardment of high-energy ions have been demonstrated to enhance the wear resistance, corrosion resistance, bioactivity and antimicrobial properties [16e18]. In recent years, sequential PIII involving two or more different metallic ions has attracted high attention because of the increased versatility with regard to the surface treatment of knee joints, dental implants, artificial hips, and so on [19,20]. For instance, Krupa et al [19] have demonstrated that sequential Ca and P ion implantation improves the biocompatibility as well as corrosion resistance of titanium and Xie et al [20] have found that titanium after water and hydrogen PIII exhibits better surface bioactivity and cytocompatibility.…”

“…In recent years, sequential PIII involving two or more different metallic ions has attracted high attention because of the increased versatility with regard to the surface treatment of knee joints, dental implants, artificial hips, and so on [19,20]. For instance, Krupa et al [19] have demonstrated that sequential Ca and P ion implantation improves the biocompatibility as well as corrosion resistance of titanium and Xie et al [20] have found that titanium after water and hydrogen PIII exhibits better surface bioactivity and cytocompatibility. Different from single-metal ion implantation, sequential implantation and co-implantation offer excellent advantages in controlling the individual concentrations and depth distributions of multiple metal ions in the near-surface of titanium [21].…”