Effect of Dose of Calcium Salts of Conjugated Linoleic Acid (CLA) on Percentage and Fatty Acid Content of Milk Fat in Midlactation Holstein Cows

Giesy, J.G.; McGuire, Mark A.; Shafii, Bahman; Hanson, Travis W.

doi:10.3168/jds.s0022-0302(02)74279-3

Cited by 72 publications

(119 citation statements)

References 13 publications

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“…It is well established that the trans-10, cis-12 CLA is the responsible isomer for MFD (Baumgard et al, 2000). In this study, daily supplementation of 4.7 g/cow of the trans-10, cis-12 CLA reduced 13% and 9% content and yield of milk fat, respectively, which is very similar to the report of Giesy et al (2002) in which supplementation of 4.4 g/day of trans-10, cis-12 CLA decreased 16.2% and 11.6% milk fat percentage and yield, respectively. However, supplementation of 4.65 g of trans-10, cis-12 CLA/day decreased milk fat content and yield by 25% (Piperova et al, 2004).…”

Section: Resultssupporting

confidence: 88%

“…A significant relationship between milk fat percentage and trans-10, cis-12 CLA content in milk was reported by Giesy et al (2002). Peterson et al (2002) summarized two studies (2005) that the passage rate of digesta may influence the degree of CLA biohydrogenation in the rumen as passage rate is associated with the level of production and intake.…”

Section: Resultsmentioning

confidence: 99%

“…Peterson et al (2002) summarized two studies (2005) that the passage rate of digesta may influence the degree of CLA biohydrogenation in the rumen as passage rate is associated with the level of production and intake. It is also plausible that the basal content of trans-10, cis-12 CLA in milk fat (which was determined by the control group yield) and the rate of increase of this CLA isomer in milk, which is dose dependent (Giesy et al, 2002;Moore et al, 2004), play a role in the magnitude of MFD. Milk protein content was reduced by E-CLA during the treatment period in comparison with the controls (29.8 v. 30.8 g/kg; Table 3; P , 0.001), while no differences in protein yields were observed.…”

Section: Resultsmentioning

confidence: 99%

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Production performance and pattern of milk fat depression of high-yielding dairy cows supplemented with encapsulated conjugated linoleic acid

Moallem

Lehrer

Zachut

et al. 2010

Animal

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Several processes have been suggested to protect lipids from bioactivity of the rumen microorganisms. The majority of experiments with conjugated linoleic acid (CLA) were conducted using calcium salts of CLA. The objectives of this study were to determine the effects of encapsulated CLA (E-CLA) that was supplemented during days 21 to 100 post partum (PP), on milk fat depression, recovery rate and performance parameters. Forty-two multiparous Israeli-Holstein cows were divided at day 21 PP into two treatment groups: (i) control -supplemented with 43 g/day per cow of calcium salts of fatty acids (FAs).(ii) E-CLA -supplemented with 50 g/day per cow of encapsulated lipid supplement providing 4.7 g/day per cow of trans-10, cis-12 CLA. Post-treatment cows were followed for recovery rate until 140 days PP. Dry matter intake (DMI) during the treatment period was reduced by 2.5%, and milk yield was enhanced by 4.5% in the E-CLA cows. Milk fat percentage and yield were reduced by 13% and 9%, respectively, in the E-CLA treatment as compared with the control. The energy-corrected milk output was 3.6% higher in the control group than in the E-CLA group. Yields of trans-10, cis-12 CLA isomer in milk was 2.13-fold higher in the E-CLA cows than in the controls. Full recovery to milk fat percentage of the control group occurred 4 to 5 weeks after cessation of the E-CLA supplementation. No differences between groups were observed in any fertility parameter that was tested. In conclusion, the E-CLA supplement decreased DMI, enhanced milk yield, and decreased energy output in milk, and was effective in depressing milk fat. Full recovery to the milk fat content, but not yield, of the control group in the E-CLA group was relatively slow and occurred 4 to 5 weeks after termination of the supplementation.

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Section: Resultssupporting

confidence: 88%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Production performance and pattern of milk fat depression of high-yielding dairy cows supplemented with encapsulated conjugated linoleic acid

Moallem

Lehrer

Zachut

et al. 2010

Animal

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“…Milk fat concentration became significantly lower in CLA-than in Ctrl-fed cows after wk 2 of lactation, although CLA feeding started 2 wk before parturition. The delay in milk fat depression is in line with previous studies (Bernal-Santos et al, 2003;Castañeda-Gutiérrez et al, 2005;Odens et al, 2007) and is probably induced by peripartal processes, because during established lactation milk fat depression occurs shortly after commencing CLA supplementation (Giesy et al, 2002, Perfield et al, 2002. Milk fat contained the trans-10,cis-12 CLA isomer at wk 3 of lactation and, therefore, it was transferred to the mammary gland during early lactation.…”

Section: Effects Of Cla On Milk Performance and Body Conditionsupporting

confidence: 89%

Supplementation of conjugated linoleic acid in dairy cows reduces endogenous glucose production during early lactation

Hötger

Hammon

Weber

et al. 2013

Journal of Dairy Science

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Trans-10,cis-12 conjugated linoleic acid (CLA) supplementation causes milk fat depression in dairy cows, but CLA effects on glucose metabolism are not clear. The objective of the study was to investigate glucose metabolism, especially endogenous glucose production (eGP) and glucose oxidation (GOx), as well as hepatic genes involved in endogenous glucose production in Holstein cows supplemented either with 50 g of rumen-protected CLA (9% trans-10,cis-12 and 10% cis-9,trans-11; CLA; n = 10) or 50 g of control fat (24% C18:2; Ctrl; n = 10) from wk 2 before parturition to wk 9 of lactation. Animal performance data were recorded and blood metabolites and hormones were taken weekly from 2 wk before to 12 wk after parturition. During wk 3 and 9 after parturition, glucose tolerance tests were performed and eGP and GOx were measured by [U-13 C] glucose infusion. Liver biopsies were taken at the same time to measure total fat and glycogen concentrations and gene expression of pyruvate carboxylase, cytosolic phosphoenolpyruvate carboxykinase, glucose-6-phosphatase, and carnitine palmitoyl-transferase 1. Conjugated linoleic acid feeding reduced milk fat, but increased milk lactose output; milk yield was higher starting 5 wk after parturition in CLA-fed cows than in Ctrl-fed cows. Energy balance was more negative during CLA supplementation, and plasma concentrations of glucose were higher immediately after calving in CLAfed cows. Conjugated linoleic acid supplementation did not affect insulin release during glucose tolerance tests, but reduced eGP in wk 3, and eGP and GOx increased with time after parturition. Hepatic gene expression of cytosolic phosphoenolpyruvate carboxykinase tended to be lower in CLA-fed cows than in Ctrl-fed cows. In spite of lower eGP in CLA-fed cows, lactose output and plasma glucose concentrations were greater in CLA-fed cows than in Ctrl-fed cows. This suggests a CLA-related glucose sparing effect most likely due to lower glucose utilization for milk fat synthesis and probably because of a more efficient whole-body energy utilization in CLA-fed cows.

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“…O aumento verificado no teor de sólidos totais (%), equivalente a 8,3%, pode ser atribuído a uma possível elevação do teor de gordura do leite, uma vez que não foram encontradas alterações no conteúdo de proteína e que a concentração de lactose dificilmente é influenciada por modificações das fontes utilizadas na formulação de dietas para animais em lactação (Mir et al, 1999;Vargas et al, 2002;Giesy et al, 2002).…”

Section: Resultsunclassified

Inclusão de fontes de óleo na dieta de cabras em lactação: produção, composição e perfil dos ácidos graxos do leite

Maia¹,

Branco²,

Mouro³

et al. 2006

R. Bras. Zootec.

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O objetivo neste trabalho foi avaliar o efeito da inclusão de fontes de óleo na dieta de cabras em lactação sobre a produção, a composição e o perfil dos ácidos graxos da gordura do leite. Foram utilizadas quatro cabras da raça Saanen (54±1,02 kg PV) aos 80 dias em lactação, canuladas no rúmen. Os tratamentos consistiram de dietas suplementadas com diferentes fontes de óleo (canola, arroz e soja) e de uma dieta controle. O delineamento experimental utilizado foi o quadrado latino 4 x 4 e os dados foram analisados utilizando-se o procedimento MIXED do SAS (2001). As diferenças entre as médias dos tratamentos foram determinadas por contrastes ortogonais, a 10% de significância. A produção e composição do leite, à exceção do percentual de sólidos totais, não foram influenciadas pela suplementação lipídica na dieta. A utilização de óleos vegetais aumentou as concentrações de ácido linoléico conjugado (CLA), 18:0, 18:1n-9, 18:2, na gordura do leite. Constatou-se diminuição das concentrações de ácidos graxos saturados (AGS) e de cadeias curta (AGCC) e média (AGCM). Houve aumento das concentrações de ácidos graxos mono (AGMS) e poliinsaturados (AGPI), de ácidos graxos de cadeia longa, de ômega-3 e 6 e da relação AGPI/AGS. A inclusão do óleo de soja na dieta, em comparação à suplementação com óleo de canola, resultou em maior concentração de AGPI e n-6, em maior relação de AGPI/AGS e n-6/n-3 e menor de 22:6n-4 no leite. O enriquecimento de dietas para cabras com óleos vegetais melhorou a qualidade do leite elevando a concentração de ácidos graxos desejáveis.

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Effect of Dose of Calcium Salts of Conjugated Linoleic Acid (CLA) on Percentage and Fatty Acid Content of Milk Fat in Midlactation Holstein Cows

Cited by 72 publications

References 13 publications

Production performance and pattern of milk fat depression of high-yielding dairy cows supplemented with encapsulated conjugated linoleic acid

Production performance and pattern of milk fat depression of high-yielding dairy cows supplemented with encapsulated conjugated linoleic acid

Supplementation of conjugated linoleic acid in dairy cows reduces endogenous glucose production during early lactation

Inclusão de fontes de óleo na dieta de cabras em lactação: produção, composição e perfil dos ácidos graxos do leite

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