Effect of Different Wavelengths on Superoxide Dismutase

Azeemi, Samina T. Yousuf; Raza, Syed Mohsin; Yasinzai, Masoom; Samad, Abdul

doi:10.1016/s2005-2901(09)60060-1

Cited by 9 publications

(6 citation statements)

References 3 publications

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“…Superoxide dismutase (SOD) is one of the most important antioxidant enzymes present in all oxygen metabolizing cells this enzyme eliminates toxins From body [31]. The antioxidant system consists of antioxidants act by scavenging the radicals directly and sustaining the activity of antioxidant enzymes as inhibiting the activities of oxidizing enzymes in intra erythrocytic parasites theleria annulata and babesia bovis [30]. Animals in our study treated with imidocarb as antbabesial drugs and antioxidant drugs as Vit.E to improve antioxidant mechanisms by increase activity of antioxidant enzymes and scavenger to lipid peroxidation and restoring to normal since Vit.E.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Erythrocytes Antioxidant Mechanisms in Bovine Babesiosis and Current Advances Treatment in Kaliobea Governorat

E.I.Radwan¹,

Hamied²,

Ali³

2013

AJIDM

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Bovine babesiosis is a febrile, tick-borne disease of cattle and buffalo, caused by one or more protozoan parasites of the genus Babesia.The term "Babesiosis" refers to the acute form. In this study we selected animals from endemic area of Babesia bigemina infection that suffered from fever, emaciated, anemia, icterus and variable weight loss. The acute form is generally characterized by rapid growth and multiplication of the parasite in blood so diagnosis of babesiosis by microscopic examination is applicable in positive infected animals. These ones were distributed in three groups; each group consists of 50 animals and we selected twenty animals healthy (not infected) as control group. The infected animals of the first group was not treated as control positive, the second group was treated with imidocarb antibabesial drug and the third group was treated with imidocarb and Vit E as antioxidant. A comparison was made between the two methods of treatment by measuring erythrocytes antioxidant mechanisms representing in (G6PD, GR-ase,SOD and MDA) and in plasma (NO and trace element as antioxidant). Blood samples were collected from all animals from jugular vein: two samples, one on anticoagulant to measure erythrocytes antioxidant mechanisms and another to measure NO and trace elements. Results showed increased values of oxidant and decreased values of antioxidant in calves buffaloes suffered from parasitic infection as compared with healthy animals that especially for values of Nitric Oxide (NO) and Malondialdehyde (MDA). So, there was an increase in oxidative markers in animals infected with babisiosis while the levels of antioxidants such as superoxide dismutase(SOD), glutathione reductase (GR-ase); Glucose-6-Phosphate Dehydrogenase(G6PD) decreased, and some trace element showed changes as well (Cu). Addition of antioxidant (Vit E) to treatment decreased oxidative effect of infection and played an important role in increase of antioxidant.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Erythrocytes Antioxidant Mechanisms in Bovine Babesiosis and Current Advances Treatment in Kaliobea Governorat

E.I.Radwan¹,

Hamied²,

Ali³

2013

AJIDM

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“…It is suggested that light treatments produce biological effects in molecules, living cells and tissues [ 10 , 11 , 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

“…Other proteins whose activity can be affected by phototherapy include superoxide dismutase (max in 644 nm), glucose oxidase (464 nm), cholesterol esterase and cholesterol oxidase, and lipase (400 nm) [ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…The effectiveness of therapy that uses wavelengths in the visible region has been shown for various medical conditions, such as dengue fever, insomnia, diabetes, psychiatric illnesses, hypertension, seasonal affective disorder (SAD), immunity, hyperacidity, cutaneous wound healing, chronic joint diseases and inflammation [ 12 , 14 , 15 , 16 , 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

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Vascular Responses following Light Therapy: A Pilot Study with Healthy Volunteers

Salon

Brix

Neshev

et al. 2023

JCM

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(1) Background: Studies have reported the effectiveness of light therapy in various medical conditions. Our pilot study aimed to assess the effect of Maharishi light therapy (MLT) on physiological parameters, such as the heart rate (HR), HR variability (HRV), blood pressure (BP), BP variability (BPV), and the retinal microvasculature of healthy participants; (2) Methodology: Thirty (14 males and 16 females) healthy, non-smoking participants between 23 and 71 years old (46 ± 18 years) were included in this randomized crossover study. Each participant was tested with a placebo (using LED light) and gem lights, 24 h apart. Hemodynamic parameters were recorded during the session, and 24 h heart rate and BP levels were assessed via mobile devices. Retinal vascular responses were captured with fundus images and the subsequent analysis of retinal vessel widths. A linear model, using repeated measures ANOVA, was used to compare the responses across the sexes and to assess the effect of the MLT; (3) Results: Changes in the central retinal artery equivalent (CRAE) (p < 0.001) and central retinal vein equivalent (CRVE) (p = 0.002) parameters were observed. CRAE and CRVE decreased under MLT and increased under the placebo condition from before to after. However, the baseline values of the participants already differed significantly before the application of any therapy, and the variation in the retinal vessel diameters was already large in the baseline measurements. This suggests that the observed effect results may only reflect naturally occurring fluctuations in the microcirculation and not the effect of MLT. Furthermore, no significant effects were observed in any other investigated parameters; (4) Conclusion: Our study with healthy participants finds significant changes in retinal parameters, but the biological variation in the baseline measurements was large to begin with. This suggests that the observed effect results only reflect naturally occurring fluctuations in the microcirculation and not the effect of MLT. However, in the future, larger studies in which MLT is applied for longer periods and/or in patients with different diseases could discover the physiological impacts of this type of therapy.

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“…The effect of different wavelengths on superoxide dismutase (SOD) has been reported [7] [8]. Thus, after presenting solid scientific reasoning behind this therapeutic mode of treatment pertaining to the activity of SOD in the presence of 644 nm radiation, a randomised controlled clinical trial has been carried out which builds a unique relationship of 644 nm irradiated SOD with the elimination of free radicals and hence the enhancement of immunity.…”

mentioning

confidence: 99%

Elimination of Free Radicals and Immunity Enhancement with 644 nm (Red Colour) Radiation: A Randomised Controlled Clinical Trial

Azeemi¹,

Shaukat²,

Qasim³

et al. 2016

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Superoxide dismutase (SOD) is an important antioxidant enzyme present in all oxygen-metabolizing cells. The effect of different wavelengths on superoxide dismutase (SOD) has been reported previously which has shown to have a remarkable effect on immune system. Thus, after presenting solid scientific reasoning behind this therapeutic mode of treatment pertaining to the activity of SOD in the presence of 644 nm radiation, a randomised controlled clinical trial has been carried out which builds a unique relationship of 644 nm irradiated SOD with the elimination of free radicals and hence the enhancement of immunity, not only for curative treatment but also as a preventive tool against all those diseases related to the elimination of free radicals to get better immune system of the human body. This study was conducted in the department of Gynecology and obstetrics at Al-Khidmat Teaching Hospital Mansoorah, Lahore, Pakistan.

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Effect of Different Wavelengths on Superoxide Dismutase

Abstract: Red color wavelength actually provides additional energy to the enzyme and hence the activation energy is lowered, compared with untreated enzyme.

Cited by 9 publications

References 3 publications

Evaluation of Erythrocytes Antioxidant Mechanisms in Bovine Babesiosis and Current Advances Treatment in Kaliobea Governorat

Evaluation of Erythrocytes Antioxidant Mechanisms in Bovine Babesiosis and Current Advances Treatment in Kaliobea Governorat

Vascular Responses following Light Therapy: A Pilot Study with Healthy Volunteers

Elimination of Free Radicals and Immunity Enhancement with 644 nm (Red Colour) Radiation: A Randomised Controlled Clinical Trial

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