Effect of Different Anesthetic Techniques on Trace Elements: TIVA vs Inhalation Anesthesia

Ceylan, Berit Gökçe; Eroğlu, Füsun; Yavuz, Lütfi; Gülmen, Şenol; Kütük, Selcen; Doğuç, Duygu Kumbul; Nazıroğlu, Mustafa; Vural, Hüseyín

doi:10.5222/jtaics.2011.1

Cited by 3 publications

(2 citation statements)

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“…They act as catalytic agents playing important roles in the cell metabolism (Jacimovic et al, 1977). Although trace elements constitute a relatively small amount of the total body tissues, they are essential to many vital processes (Ceylan et al, 2011). The levels of these trace elements in human body are under the influence of several factors.…”

Section: Introductionmentioning

confidence: 99%

“…Zn deficiencies induce growth failure, hypogonadism, impaired wound healing, and genetic disease. Copper (Cu) is an essential micronutrient required for all life processes; it is a transition metal and is involved in a variety of biological processes (Ceylan et al, 2011). Several studies have reported that interactions between Al and essential elements, such as Fe, Cu, and Zn, may be involved in the toxic effects of Al (Guo et al, 2002; Yang et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

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Effects of aluminum chloride on some trace elements and erythrocyte osmotic fragility in rats

Öztürk

Özdemir

2013

Toxicol Ind Health

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Aluminum (Al) is a nonessential, toxic element to which humans are constantly exposed as a result of an increase in industrialization and improving technology practices. The aim of the study was to investigate the effects of different durations and doses of Al exposure on serum and tissue element levels and erythrocyte osmotic fragility in rats. A total of 40 male Wistar Albino rats were divided into five groups: control, group I (3 weeks, 8 mg/kg), group II (6 weeks, 8 mg/kg), group III (3 weeks, 16 mg/kg), and group IV (6 weeks, 16 mg/kg). Al chloride (AlCl3) was injected intraperitoneally (i.p.) five times a week. At the end of the experimental period, levels of Al, iron (Fe), copper (Cu), and zinc (Zn) in serum, liver, and kidney tissues were measured using inductively coupled plasma optical emission spectrometry. Osmotic fragility was determined using a spectrophotometer. The results of the experiment indicate that Al induced a statistically significant increase in Al and Fe concentrations in liver and serum as well as in Cu in the kidney. The Fe concentration in serum and kidney tissues was significantly lower in all the groups. As a result of our study, it may be concluded that tissue Al accumulation may lead to an increase in osmotic fragility of erythrocytes and abnormal trace element levels.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of aluminum chloride on some trace elements and erythrocyte osmotic fragility in rats

Öztürk

Özdemir

2013

Toxicol Ind Health

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Stromer¹,

Michaeli²,

Sandner‐Kiesling³

2013

European Journal of Anaesthesiology

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Editor,The preoperative assessment of the likelihood of a postoperative cardiac event is complex. 1 The Revised Cardiac Risk Index (RCRI) is a commonly used scoring system for the stratification of cardiac risk of patients undergoing major non-cardiac surgery. 2 The RCRI scores patients according to six clinical categories: high-risk surgery (thoracic, abdominal and supra-inguinal vascular surgery); history of ischaemic heart disease (IHD); history of congestive heart failure; cerebrovascular disease; insulin-dependent diabetes; and renal failure. Since the publication of the original article in 1999, the RCRI has become a widely used stratification tool for cardiac risk. A recent meta-analysis has examined the predictive value of the RCRI in these studies. 3 It concluded that the RCRI performed moderately well at discriminating between low and high perioperative risk. However, the authors felt that it performed poorly in vascular cohorts, and that the studies included were of variable quality. This report highlights the need for further studies evaluating the RCRI.We report the results of a single centre observational study of consecutive patients undergoing major vascular surgery (aortic surgery, infra-inguinal bypass surgery, amputation). Ethical approval for this study [REC reference number 04/193(1)] was provided by the West of Scotland Research Ethics Committee (Chairperson Dr A Binning) on 2 March 2004. All patients gave written consent to the study. The patients were preoperatively scored according to the RCRI criteria. 2 The presence of other risk factors was obtained from the patient's history and medical records. Operations were recorded as elective or expedited (within 3 weeks of initial presentation). Patients operated as an emergency, within 24 h of an unplanned admission, were excluded. Postoperative screening for cardiac events was performed by daily clinical assessment, serial ECGs and troponin I measurement. The primary outcomes were major adverse cardiac event (MACE) (non-fatal myocardial infarction and cardiac mortality) and all-cause mortality. Patients were followed-up for 6 weeks following surgery. Statistical analysis was performed using SPSS (Version 15) statistical software package (SPSS, Chicago, IL). Categorical variables are presented with totals and percentages, and analysed with Chi-square, Fisher's exact test or Mann-Whitney test as appropriate. Receiver operating characteristic (ROC) curves were plotted to model the efficacy of the RCRI. The area under the curve (AUC) was calculated.A total of 252 patients were included in the study: aortic surgery 25.8%; bypass surgery 39.7%; and lower limb amputation 34.5%. Thirty-nine patients (15.5%) had a postoperative MACE, and 20 patients (7.9%) died within the postoperative 6-week period. Applying the RCRI to the cohort as a whole, the rate of MACE for RCRI class 1, 2, 3 and 4 was 13.4, 14.9, 18.6 and 16.7%, respectively (P ¼ 0.858) (Table 1). Similarly, the rate of perioperative mortality for these groups was 7.3, 9.2, 6.8 and 8.3%, r...

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An alternative way of managing acute pain in patients who are in buprenorphine opioid substitution therapy programs

Huxtable

Macintyre²

2013

European Journal of Anaesthesiology

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Effect of Different Anesthetic Techniques on Trace Elements: TIVA vs Inhalation Anesthesia

Cited by 3 publications

References 8 publications

Effects of aluminum chloride on some trace elements and erythrocyte osmotic fragility in rats

Effects of aluminum chloride on some trace elements and erythrocyte osmotic fragility in rats

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An alternative way of managing acute pain in patients who are in buprenorphine opioid substitution therapy programs

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