Effect of Dietary Supplementation of Biological Curcumin Nanoparticles on Growth and Carcass Traits, Antioxidant Status, Immunity and Caecal Microbiota of Japanese Quails

Abstract

This study was planned to evaluate the impact of different nano-curcumin levels on the growth rate, carcass, blood chemistry and caecal microbes of growing quail. A total of 270 Japanese quails at one-week-old were distributed to six equal groups; each group consisted of 45 unsexed birds with five replications (nine quails each). The 1st group was fed a basal diet, whereas the 2nd, 3rd, 4th, 5th and 6th groups were fed diets containing nano-curcumin (0.1, 0.2, 0.3, 0.4 and 0.5 g/kg diet, respectively). Nano-curcumin levels significantly increased (p ≤ 0.0001) body weight at 3 weeks and 5 weeks of age. Body weight gain during 1–3, 3–5 and 1–5 weeks of age was significantly increased (p < 0.0001) in groups treated with nano-curcumin levels (except at 0.3 g/kg; 1–3 weeks) compared to control. During 1 to 5 weeks, feed intake was decreased (p < 0.0001) in birds receiving nano-curcumin (0.1, 0.3 and 0.4 g/kg) diets. The best values of feed conversion ratio were recorded for the 0.4 g nano-curcumin-treated group. Carcass traits were not affected Nano-curcumin levels. The inclusion of nano-curcumin (0.2, 0.3 or 0.5 g/kg) significantly increased serum TP (p = 0.0004), albumin (p = 0.0078) and globulin (p < 0.0001). Quails fed with nano-curcumin (0.2 g/kg) exhibited the highest SOD and GSH activities, serum IgG and IgM concentrations and complement values compared to control. The addition of any level of nano-curcumin in the quail diet also significantly improved the lipid profile. In conclusion, supplemental nano-curcumin had beneficial impacts on growth, lipid profile, blood constituents, antioxidant indices, and immunity of growing quail, as well as increasing counts of lactic acid bacteria and reducing pathogenic bacteria.

The Strategy of Boosting the Immune System Under the COVID-19 Pandemic

“…For instance, curcumin and resveratrol have been evidenced to inhibit the signaling pathway of nuclear factor-kappa β (NF-κβ) and thereby inhibit the release of the proinflammatory cytokine TNF-α ( 154 ). Curcumin has been reported to have a role in activation and proliferation of B and T lymphocytes, increase the antibody titer against some viruses, enhance innate immunity in challenged animals, improve the immune response by increasing leucocyte count and phagocytic activates, and stimulate the function of plasma lysozyme and increased immunoglobulin ( 146 , 155 , 156 ). Curcumin could also improve the functions of T and B lymphocytes, monocytes, heterophils, macrophages, and dendritic cells and reduce the inflammatory responses ( 157 ).…”

“…Phytogenic feed additives exert their favorable health improving effects owing to their content of active substances such as polyphenols and secondary metabolites. Polyphenols are found in vegetables, grains, fruits, and green and black tea in different parts of the plant (leaves, roots, flowers, seeds, and fruits) to protect the plant immune system against UV radiation and pests (141)(142)(143)(144)(145)(146)(147)(148)(149)(150)(151).…”

Effects of Chemical and Natural Additives on Cucumber Juice’s Quality, Shelf Life, and Safety

“…After that, 1 mL of each dilution was placed in sterile disposable Petri dishes (sterilin) in triplicates. At about 44 to 50 • C, the number of different bacteria was determined by using specified media [44][45][46]. Colon bacteria were counted on MacConkey agar and brooded at 37 • C for 24 h. The total viable count (TVC) on Agar media was counted and incubated at 25 m, for a period of 72 h. Microbiological results were converted to logarithms (CFU/g).…”

Impacts of Green Coffee Powder Supplementation on Growth Performance, Carcass Characteristics, Blood Indices, Meat Quality and Gut Microbial Load in Broilers

“…Serial dilutions up to 10 7 were prepared. Enterococcus spp., coliforms and total bacteria were counted according to Sheiha et al [39] and Reda et al [40]. Total coliforms were counted according to Richard et al [41] by MacConkey agar medium.…”